Thyroid Disease, Pregnancy, and Selenium Supplementation

Savastano, Giovanna; Negro, Valentina; Pompeo, Damiana; Sorrenti, Sara; Gabriela, Paola; Brunelli, Roberto; Piccioni, Maria Grazia

doi:10.1007/s13669-021-00314-3

Cited by 2 publications

(2 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For this reason, the antioxidant properties associated with Se have drawn great attention [237]. Thus, a wide range of trials has been conducted to determine whether Se supplementation could influence the evolution of these diseases [225,236,[238][239][240].…”

Section: Selenomethionine and Autoimmune Thyroid Diseasesmentioning

confidence: 99%

“…Over the last years, several literature reports have indicated that this element, in combination with myo-inositol, has a beneficial effect as it can reduce the thyroid-stimulating hormone (TSH) and the antithyroid autoantibodies levels, thus decreasing the risk of progression to hypothyroidism in AITDs patients [225,237,[241][242][243][244][245]. Moreover, the protective effect of Se supplementation on thyroid autoimmunity during and after pregnancy has been studied [5,228,238,239]. In this regard, the SERENA study has evaluated the effect of SeMet on AITDs in euthyroid pregnant women with positive antithyroid antibodies.…”

Section: Selenomethionine and Autoimmune Thyroid Diseasesmentioning

confidence: 99%

See 1 more Smart Citation

Seleno-Metabolites and Their Precursors: A New Dawn for Several Illnesses?

et al. 2022

View full text Add to dashboard Cite

Selenium (Se) is an essential element for human health as it is involved in different physiological functions. Moreover, a great number of Se compounds can be considered potential agents in the prevention and treatment of some diseases. It is widely recognized that Se activity is related to multiple factors, such as its chemical form, dose, and its metabolism. The understanding of its complex biochemistry is necessary as it has been demonstrated that the metabolites of the Se molecules used to be the ones that exert the biological activity. Therefore, the aim of this review is to summarize the recent information about its most remarkable metabolites of acknowledged biological effects: hydrogen selenide (HSe−/H2Se) and methylselenol (CH3SeH). In addition, special attention is paid to the main seleno-containing precursors of these derivatives and their role in different pathologies.

show abstract