Thyroid Disorders in Patients of Type 2 Diabetes Mellitus

Uppal, Vibha; Vij, Chittranjan; Bedi, Gurdeep Kaur; Vij, Anil; Banerjee, Basu Dev

doi:10.1007/s12291-012-0293-9

Cited by 35 publications

(37 citation statements)

References 19 publications

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“…The average PPBS in this population is 212 mg/dl with 95% of them in between 196-228 mg/dl which is almost similar to previous study. Distribution of HbA1C shows 95% (2 SD) of population are within 8.02-8.96%, well above the good control (<7%) consistent with Vibha Uppal et al 25 Distribution of FT4 level is normal in maximum no of patients whereas that of FT3 is towards lower range of normal value. But TSH level is significantly abnormal reflecting underlying thyroid abnormality in maximum population, which in accordance with Celani et al 26 In our study we found a low T3 state with significantly increased fasting blood glucose, HbA1C.…”

Section: Discussionsupporting

confidence: 85%

A study of prevalence of primary hypothyroidism in recently diagnosed type 2 diabetes mellitus in a tertiary care hospital

Mukherjee

Datta

et al. 2015

Int J Sci Rep

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Background: The association between thyroid dysfunction and DM has long been recognized, although the prevalence of thyroid dysfunction among diabetes population varies in different studies. This study destined to know the prevalence of thyroid dysfunction of recently diagnosed type 2 diabetes mellitus patients. Methods: Retrospective chart review of 60 patients with type 2 diabetes mellituswas done. Total 60 patients (male 51, female9) fulfillingdiagnostic criteria for diabetes mellitus according to ADA (American Diabetes Association) criteria were analysed by doing Thyroid Function Test (FT4,TSH).Results: 75% of patients have the biochemical features of thyroid dysfunction. Subcategorically in descending order of frequency they are - Subclinical hypothyroidism (33.33%) (defined by no symptoms or clinical fetures of hypothyroidism but biochemically TSH level in the range of above 5 mIU/ml but below 10 mIU/ml with normal FT4 level), 15% of patients each for overt hypothyroidism (either clinical features or Biochemically TSH >10 mIU/ml or FT4 below normal), and subclinical hyperthyroidism (only biochemical low level of TSH <0.34 mIU/ml in this study) and 11.667% patients show the features of clinical hyperthyroidism (clinical or FT4 level well above normal range along with low TSH).Conclusions: Avery high prevalence of thyroid dysfunction in this part of world in contrast to Europe & US suggest routine screening for thyroid disorder in recently diagnosed type 2 diabetes mellitus.

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Section: Discussionsupporting

confidence: 85%

A study of prevalence of primary hypothyroidism in recently diagnosed type 2 diabetes mellitus in a tertiary care hospital

Mukherjee

Datta

et al. 2015

Int J Sci Rep

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“…Additionally, we found that the trend of hypothyroidism increased significantly with increasing fasting blood glucose (Figure-1). The associations between hypothyroidism and diabetes have been reported in other studies and in other forms of diabetes [6,7,[18][19][20][21][22]. A study found a higher TSH level in patients with metabolic syndrome suggesting that hypothyroidism may be a risk factor for it [23].…”

Section: Discussionmentioning

confidence: 80%

Prevalence of hypothyroidism in different occupational groups of Bangladeshi population

Sayeed¹,

Mohsena²,

Haq³

et al. 2020

IMC J Med Sci

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Background and aims: Hypothyroidism is a common global endocrine disorder. The magnitude of hypothyroidism at community level in Bangladesh is unknown except some clinic-based studies. The present study was undertaken to determine the prevalence of hypothyroidism in different occupational groups of Bangladeshi population and to assess the risks related to it. Study design: Three occupational groups (house-wives, college students, rickshaw-pullers) of native Bangladeshi population were purposively selected. Investigations included socio-demography, anthropometry, blood pressure and biochemistry [fasting blood glucose, lipids, thyroid stimulating hormone (TSH) and free thyroxin (FT4)]. Laboratory tests were done only on a randomized sample of participants. Results: Overall, 626 (M/F=123 / 503) participants with a mean age of 35.9 (34.75 – 37.02) years volunteered. The mean values of all participant for TSH and FT4 were 2.08 (95%CI: 1.72 – 2.45) μiu/ml and 13.04 (95CI:12.86 – 13.22) pmol/L respectively. The third percentile of TSH ranged from 0.42 to 0.46 μiu/ml and 97th percentile ranged from 5.16 to 5.24 μiu/ml. For FT4, the 3rd and the 97th percentile were 10.3 and 16.41 pmol/L, respectively. The prevalence of hypothyroidism in both sexes was 7.0% (M/F=4.1/8.3%). Occupational groups, sex and increasing age, obesity, blood pressure, and lipids showed no association with hypothyroidism. Hyperglycemia was proved to be a significant risk for hypothyroidism (prevalence in diabetic vs. non-diabetic was12.9% vs. 5.5%, p = 0.04; FBG was correlated with TSH, r = 0.138, p <0.001). Conclusions: It is concluded that the prevalence of hypothyroidism was almost equal to other studies. Hypothyroidism was not related to increasing age, obesity, blood pressure and lipids. It was found to affect all sexes, all social classes and all occupational groups. Hyperglycemia was evidently found as significant risk for hypothyroidism. Ibrahim Med. Coll. J. 2019; 13(2): 9-17

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“…11,12 The logical explanation of the lower prevalence is due to iodine replete status of the middle east countries and difference in thyroid function assay methods. [13][14][15][16][17] The explanation of increased prevalence reported in most of the Indian studies may be due to our country is having mixed population with iodine deficient and iodine replete status. There may be a genetic or environmental (goitrogens) angle of explanation too.…”

Section: Discussionmentioning

confidence: 99%

Study of prevalence of thyroid dysfunction in type 2 diabetes mellitus

et al. 2018

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Background: Type 2 diabetes mellitus (T2DM) is associated with increased incidence of thyroid dysfunction (TD). The coexistence of thyroid dysfunction in T2DM patient is an important barrier in achieving treatment goal. The study regarding prevalence of TD in T2DM has not been done in patients of Eastern Uttar Pradesh. The present study was aimed to know the prevalence of thyroid dysfunction in T2DM in patients of Eastern Uttar Pradesh.Methods: This is an observational cross sectional prevalence study of thyroid dysfunction in 250 diagnosed T2DM patients deleat diagnosed based on ADA criteria attending the department of medicine Baba Raghav Das Medical College, Gorakhpur, Uttar Pradesh, Study was India, done over a period of 1 year. Thyroid dysfunction was classified on the basis of ATA criteria. All subjects underwent a detailed history, clinical examination and relevant biochemical tests.Results: The prevalence of thyroid dysfunction in T2DM patients was found to be 20.4% in this study.Conclusions: The prevalence of thyroid dysfunction was found to be higher in type 2 diabetes mellitus patients in comparison to general population as mentioned in different literature.

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Thyroid Disorders in Patients of Type 2 Diabetes Mellitus

Cited by 35 publications

References 19 publications

A study of prevalence of primary hypothyroidism in recently diagnosed type 2 diabetes mellitus in a tertiary care hospital

A study of prevalence of primary hypothyroidism in recently diagnosed type 2 diabetes mellitus in a tertiary care hospital

Prevalence of hypothyroidism in different occupational groups of Bangladeshi population

Study of prevalence of thyroid dysfunction in type 2 diabetes mellitus

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