Thyroid Functions in Relation to Reproduction of Mammals and Birds

Maqsood, M.

doi:10.1111/j.1469-185x.1952.tb01366.x

Cited by 69 publications

(20 citation statements)

References 151 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is, none the less, considerable evidence that the alteration in gonadotrophic potency in the change from eu-thyroidism to hypo-or hyperthyroidism is due to a shift in the follicle stimulating homone-luteinizing hormone ratio and in the rate at which these hormones are secreted (see Maqsood, 1952, for a review). Of considerable interest are the data obtained by Meites & Chandrashaker (1949) (reported by Nalbandov, 1976) who rendered male rats and mice hypo-or hyperthyroid and then treated them with a standard dose of a gonadotrophic hormone.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Carbimazole on Growth and Sexual Maturity in the Pullet

Shanawany

Morris

1987

Exp Physiol

View full text Add to dashboard Cite

Carbimazole (100 mg/kg diet) was fed to pullets from 8 to 12 or from 12 to 16 weeks of age. Pullets fed carbimazole from 8 to 12 weeks of age matured about 12 d earlier and produced more eggs between 17 and 22 weeks of age. Their body weights and feed intake were significantly lower than those of normal birds. Feeding carbimazole from 12 to 16 weeks of age had no significant effect on the birds except during the course of treatment where their feed consumption was less than that of the controls.

show abstract

Section: Discussionmentioning

confidence: 99%

The Effect of Carbimazole on Growth and Sexual Maturity in the Pullet

Shanawany

Morris

1987

Exp Physiol

View full text Add to dashboard Cite

show abstract

“…In recent years, the effect of altered thyroid function on reproductive performance has been extensively investigated (see review by Maqsood, 1952), but the possible influence of variations in gonadal function on thyroid activity is less well understood. This paper is concerned with one aspect of the problem-the influence of various gonadal hormones on thyroid activity.…”

mentioning

confidence: 99%

The effects of some gonadal hormones on thyroid activity in the rabbit

Brown-Grant¹

1955

The Journal of Physiology

View full text Add to dashboard Cite

The interrelationship of the thyroid gland and the gonads has been recognized for many years by clinical endocrinologists, but the experimental study of their interaction has not kept pace with clinical observation. In recent years, the effect of altered thyroid function on reproductive performance has been extensively investigated (see review by Maqsood, 1952), but the possible influence of variations in gonadal function on thyroid activity is less well understood. This paper is concerned with one aspect of the problem-the influence of various gonadal hormones on thyroid activity. MATERIALS AND METHODSYoung adult male and female rabbits of mixed breeds (2.2-3-5 kg body wt.) were used. The majority were Chinchilla rabbits. The animals were kept in a temperature-controlled animal room at 28°C and fed a pellet diet (M.R.C. diet no. 18) and tap water ad lib. All females were isolated for at least 3 weeks after arrival before any experiments were begun so as to exclude any pregnant or pseudo-pregnant animals.Thyroid activity was studied by means of the 'release curve' technique previously described (Brown-Grant, von Euler, . Starting 48 hr after a subcutaneous injection of a tracer dose of carrier-free radio-iodine, twice daily counts were made over the thyroid region in the unanaesthetized animal. After correction for isotope decay, these counts, expressed as a percentage of the counting rate at 0 hr (48 hr after injection) were plotted semi-logarithmically against time yielding a straight line whose slope represents the rate of release of '3II-labelled thyroid hormone from the gland. Following a preliminary control period, the effect of injections of various gonadal hormones on the rate of release can be studied. After a period of hormone treatment, a further period of control observations completed the experiment. The dose of radioiodine used in most experiments was 3,c. For some of the longer experiments on the effects of treatment with various combinations of hormones a dose of 6 pc was used. For further details of the method and apparatus, the paper referred to above should be consulted.The following hormones were used in these experiments; all were administered by subcutaneous injection in a single daily dose. Actual doses are given in the relevant sections of the text. Stilboestrol, 1 or 5 mg/ml.; hexoestrol, 5 mg/ml.; progesterone, 2 or 5 mg/ml. (British Drug Houses); testosterone propionate, 5 mg/ml.; oestradiol monobenzoate, 1 mg/ml.; oestrone, 1 mg/ml.; deoxycorticosterone acetate, 5 mg/ml., and cortisone acetate, 5 mg/ml. (Organon Laboratories).

show abstract

“…Administration of T 4 results in precocious sexual development in several mammalian species (Maqsood, 1952 (Hutson and Stocco, 1981 ).…”

Section: Introductionmentioning

confidence: 99%

“…Thyroid hormones have a role in the reproductive physiology of male mammals (see Maqsood, 1952;Chandrasekar et al, 1985). Administration of T 4 results in precocious sexual development in several mammalian species (Maqsood, 1952 (Hutson and Stocco, 1981 ).…”

Section: Introductionmentioning

confidence: 99%

Plasma thyrotropin concentration in the male pig: profile from birth to puberty and the effect of season and social environment in the young adult

Vl¹,

Jc²,

Jl³

et al. 1991

Reprod. Nutr. Dévelop.

View full text Add to dashboard Cite

Thyroid Functions in Relation to Reproduction of Mammals and Birds

Cited by 69 publications

References 151 publications

The Effect of Carbimazole on Growth and Sexual Maturity in the Pullet

The Effect of Carbimazole on Growth and Sexual Maturity in the Pullet

The effects of some gonadal hormones on thyroid activity in the rabbit

Plasma thyrotropin concentration in the male pig: profile from birth to puberty and the effect of season and social environment in the young adult

Contact Info

Product

Resources

About