Thyroid Nodule Radiofrequency Ablation: Complications and Clinical Follow Up

Lim, James; Kuo, Jennifer H.

doi:10.1016/j.tvir.2022.100824

Cited by 25 publications

(8 citation statements)

References 35 publications

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“…3,4 When comparing thyroidectomy to RFA, studies report higher patient satisfaction and decreased duration of hospital stay. 5,6 It is, however, still important to consider all the risks and complications of any procedure. Although RFA is a newer technique in the United States the existing literature report major complications up to 3.8% and minor complications up to 16.8%.…”

Section: Discussionmentioning

confidence: 99%

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Cutaneous fistula formation after thyroid nodule rupture: A rare complication after radiofrequency ablation

Bastien,

Amin,

Moses

et al. 2024

Head & Neck

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BackgroundWith innovative treatment options such as radiofrequency ablation (RFA) for thyroid nodules, new complications are being identified. It is important to define and delineate complications in order to counsel patients appropriately about treatment options and their associated risks and benefits.MethodsA 46‐year‐old male presented with a left thyroid nodule (6.5 cm). Fine needle aspiration results were benign. He started to develop intermittent dyspnea and underwent one RFA procedure. Approximately 6 days post‐RFA, the neck area was raised and red with blister. The skin overlying the blister underwent eventual dehiscence with fluid spillage. Several months later, MRI imaging showed substernal extension with tracheal deviation.ResultsA left thyroid lobectomy was performed with cutaneous excision and successful closure of a fistula.ConclusionsThis is the first reported case of a thyroid nodule rupture following RFA which manifested into a thyro‐cutaneous fistula and required surgical intervention.

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Section: Discussionmentioning

confidence: 99%

“…Concurrently, RFA appears to confer a lower incidence of hypothyroidism 3,4 . When comparing thyroidectomy to RFA, studies report higher patient satisfaction and decreased duration of hospital stay 5,6 . It is, however, still important to consider all the risks and complications of any procedure.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous fistula formation after thyroid nodule rupture: A rare complication after radiofrequency ablation

Bastien,

Amin,

Moses

et al. 2024

Head & Neck

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“…The use of expanded ablation treatment is prone to cause thermal damage to the blood vessels and nerves of patients, resulting in articulation disorders, nodule rupture and other complications 16 , 17 . The incidence of major complications in the application of RFA in the thyroid nodule has been reported to be as high as 3.8% 18 , and another study of RFA applied to the thyroid nodules in children reported complication rates as high as 4.8% and found higher VPR in nodules with a predominantly cystic component 14 . Therefore, it makes sense explore the risk factors of thyroid nodule recurrence after RFA and take corresponding intervention measures to improve the prognosis of the disease.…”

Section: Discussionmentioning

confidence: 99%

Risk factors of recurrent thyroid nodules after radiofrequency ablation

Xia,

Fu,

Qian

et al. 2023

Afr H. Sci.

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Objective: To investigate the risk factors of thyroid nodule recurrence after radiofrequency ablation (RFA). Methods: The medical record information of 120 patients with thyroid nodules admitted to our hospital from June 2019 to April 2022 was retrospectively analysed. All participants received RFA treatment. According to the results of the postoperative thyroid ultrasoundexamination (USG), the patients were divided into the recurrence group (R, N=16) and the non-recurrence group (NR,N=104). Binary logistic regression analysis was performed to identify the independent risk factors of thyroid nodule recurrenceafter RFA. The receiver operating characteristic (ROC) curve was used to analyse the value of the forecast of each independentfactor and combined model for thyroid nodule recurrence after RFA. Results: During the follow-up period, 16 patients recurred, and the recurrence rate was 13.33%. Univariate regression analysisshowed that whether the nodules are solitary (WNS), nodule diameter (ND), the degree of risk of nodular location (DRN),recurrent laryngeal nerve (RLN) injury were associated with thyroid nodule recurrence after RFA (P<0.05). Binary logisticregression analysis showed that WNS, ND, DRN and RLN injury were independent risk factors for the recurrence of thyroidnodules after RFA (P<0.05). ROC analysis of independent factors and combined model showed that solitary nodules, nodulediameter and nodule location risk degree had diagnostic value, while RLN injury had no predictive value. The combined modelis more predictive than the independent factors. Conclusions: The risk factors of recurrent thyroid nodules after radiofrequency ablation are related to WNS, ND, DRN and so on, which should be paid attention to and preventive measures should be taken. Keywords: Thyroid nodules; radiofrequency ablation; recurrence; risk factors.

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“…RFA complications range from pain, skin burns, and hematoma formation to adjacent structural injuries and nodule rupture. 3,4 Thyroid dysfunction in the long term was documented, in which patients with diabetes or lower baseline TSH levels are prone to thyrotoxicosis. 4 In the current literature, only one case of post-RFA hyperthyroidism requiring treatment was documented by McAninch et al In this case, symptomatic hyperthyroidism developed 8 weeks post-RFA and was later diagnosed as Graves' disease requiring thyroidectomy.…”

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confidence: 99%