Thyroid Nodules in Children

Pittock, Siobhán

doi:10.1007/978-3-319-59474-3_14

Cited by 1 publication

(2 citation statements)

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“…Preoperative FNAC was performed in 27.1% of cases (Table 1). There were Bethesda category II ("benign") in 54.8% (23). Bethesda category V ("suspicious for malignancy") was diagnosed in 16.7% (7), and Bethesda category IV ("suspicious for follicular neoplasm") and Bethesda category VI ("malignancy") were diagnosed in equally 9.5% (4).…”

Section: Resultsmentioning

confidence: 99%

“…However, in adult cohorts, as well as in children and adolescents, FNAC bears limitation for the assessment of follicular lesions and because of the new defined entity "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) even for papillary thyroid carcinoma [16]. Consequently, the true nature of a "suspicion nodule" remains undetermined in many cases preoperatively [15,[17][18][19][20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

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Thyroid surgery in children and young adults: potential overtreatment and complications

Staubitz

Bode

Poplawski

et al. 2020

Langenbecks Arch Surg

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Purpose Thyroid nodules in the pediatric population are more frequently associated with malignant thyroid disease than in adult cohorts. Yet, there is a potential risk of surgical overtreatment. With this single center study, an analysis of potential overtreatment for suspected malignant thyroid disease in children and young adults was aimed for. Methods In a period from 2005 to 2018, 155 thyroid operations in children and young adults performed at the University Medical Center Mainz, Germany, were analyzed (patient age 3-20 years, 117 female). Cases were categorized for preoperative diagnosis: non-malignant (group I, n = 45) and malignant thyroid disease (group II, n = 110). Postoperative parameters (histology, complication rates) were assessed and compared between groups. Results 91.1% of group I were histologically benign. 44.5% of group II harbored malignancy. Permanent hypoparathyroidism was documented in group I (2.7%) and in group II (1.4%, p = 1.000). Wound infections were absent in group I but observed in group II (0.9%, p = 1.000). Transient vocal cord palsy was recorded only in group I (2.3%, 2/85 vs. 0/177 nerves at risk, p = 0.104). Permanent vocal cord palsies were absent. Conclusion Preoperative diagnoses were correct in over 90% of group I and in nearly 45% of group II. The high proportion of carcinomas in group II ruled out the issue of potential overtreatment. The risk of severe postoperative complications was equally low in both patient groups.

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Section: Resultsmentioning

confidence: 99%