Thyroid storm induced by aspirin intoxication and the effect of hemodialysis: A case report

Abstract

Thyroid dysfunction is one of the serious consequences of an overdose of acetaminophen, aspirin, or nonsteroidal antiinflammatory drugs. The management of such consequences remains a medical challenge. A variety of thyroid abnormalities are common in clinical practice and can, in many cases, be accurately diagnosed and managed by the primary care physician. This case study covers an aspirin overdose causing thyroid storm that was treated successfully with hemodialysis.

Thyroid Storm: Clinical Manifestation, Pathophysiology, and Treatment

“…Infection [6] Vigorous palpation of thyroid gland [30] Acute medical illness Subacute thyroiditis [31] Acute psychosis [32] Thyroxine overdosage [33] Nonthyroidal surgery [18] Aspirin intoxication [34] Parturition [35] Hydatidiform mole [36] Trauma [37] OP poisoning [38] Discontinuation of antithyroid drugs [39] Neurotoxins [40] After radioactive iodine therapy [41] Cytotoxic chemotherapy [42] Post-thyroidectomy [43] After high dose of iodine administration [44] Iodinated radiographic contrast agents [45] of an exaggerated feature of hyperthyroidism accompanied by manifestations of multiorgan dysfunction, with the presence of an acute precipitating factor [46]. Symptoms, signs, and clinical features are listed in Tables 2-4 respectively.…”

Diagnosis and Management of Thyrotoxicosis

“…If a primary infectious cause is supposed, early broad-spectrum antibiotics should not be forgotten and must be initiated as soon as possible. Patients who display refractory life-threatening symptoms must undergo hemodialysis after medical management has failed [20] . The diagnosis can be challenging because signs and symptoms can mimic many other disease states resulting in an inaccurate diagnoses and management.…”