Thyroidectomy remains an effective treatment option for Graves’ disease

Weber, Kaare J.; Solórzano, Carmen C.; Lee, Jane K.; Gaffud, Michael J.; Prinz, Richard A.

doi:10.1016/j.amjsurg.2005.10.043

Cited by 66 publications

(44 citation statements)

References 24 publications

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“…Weber et al [21] observed either improvement or subsidence of eye symptoms after surgery. In contrast, our patients -despite their previous thyroidectomywere still hyperthyroid and, for that reason, had been treated with methimazole or 131-I before admission to our Department to treat their GO exacerbation.…”

Section: Discussionmentioning

confidence: 97%

Wcześniejsze leczenie choroby Gravesa lekami tyreostatycznymi lub radiojodem nie wpływa na skuteczność leczenia immunosupresyjnego orbitopatii tarczycowej

Jagiełło-Korzeniowska¹,

Sokołowski

Krzentowska-Korek³

et al. 2016

Endokrynologia Polska

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Introduction: We studied the efficacy of immunosuppressive treatment of GO in a group of patients who had been treated with antithyroid drugs (the ATD group) and in another group that had undergone radioiodine therapy (the 131-I group). Material and methods: A total of 214 patients with exacerbation of GO were studied; the ATD group consisting of 168 patients, and the 131-I group consisting of 46 patients. All patients were treated with methylprednisolone IV pulses (total dose 8.0 g) followed by orbital irradiation (20 Gy in 10 fractions). CAS and IO indices, TSH, fT4, and TRAb levels were evaluated prior to, and 1, 6, and 12 months after treatment.

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Section: Discussionmentioning

confidence: 97%

Wcześniejsze leczenie choroby Gravesa lekami tyreostatycznymi lub radiojodem nie wpływa na skuteczność leczenia immunosupresyjnego orbitopatii tarczycowej

Jagiełło-Korzeniowska¹,

Sokołowski

Krzentowska-Korek³

et al. 2016

Endokrynologia Polska

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“…Thyroidectomy (mostly subtotal) is the oldest treatment modality of Graves' hyperthyroidism and in most cases it is effective in ocular condition improvement [52]. In rare situations temporary exacerbation of ophthalmopathy may occur.…”

Section: Management Of Thyroid-associated Ophthalmopathy In Children mentioning

confidence: 99%

An update on thyroid-associated ophthalmopathy in children and adolescents

Szczapa-Jagustyn¹,

Gotz‐Więckowska²,

Kocięcki³

2016

Journal of Pediatric Endocrinology and Metabolism

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“…Surgical therapy undoubtedly leads to an immediate (100 % of cases [6]) and permanent (92 % of cases [8]) resolution of hyperthyroidism, and reduces the possible progression of ophthalmopathy, resulting in a rapid clinical improvement. It also minimizes the risk of malignancy in patients with concomitant GD and thyroid nodules [9].…”

Section: Introductionmentioning

confidence: 99%

Does thyroid surgery for Graves’ disease improve health-related quality of life?

et al. 2012

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Purpose Graves' disease can induce alterations of the psychosocial well-being that negatively influence the overall well-being of patients. Among the current treatments, surgery has limited indications, and its impact on the health-related quality of life has not been well clarified. The aim of this study was to assess the impact of surgery on the quality of life. Methods Fifty-seven patients who underwent total thyroidectomy for Graves' disease in our surgical unit between April 2002 and December 2009 were administered a questionnaire concerning four issues: organic alterations and clinical manifestations, neurovegetative system disturbances, impairment of daily activities, psychosocial problems. Patients were retrospectively questioned after thyroidectomy about the presence of these symptoms in both the pre and postoperative periods. Results There was a significant improvement after surgery in all four areas. Organic manifestations and psychosocial problems had higher average improvements, as did some aspects of the neurovegetative system and difficulties in undertaking daily activities. There were no reports of a worsening of symptoms. Conclusions Surgery resolved the hyperthyroidism in 100 % of cases, and was associated with a quality of life improvement of about 70 % in the patients. Surgery can therefore provide an immediate and effective resolution of Graves' disease, with benefits in health-related quality of life.

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Thyroidectomy remains an effective treatment option for Graves’ disease

Cited by 66 publications

References 24 publications

Wcześniejsze leczenie choroby Gravesa lekami tyreostatycznymi lub radiojodem nie wpływa na skuteczność leczenia immunosupresyjnego orbitopatii tarczycowej

Wcześniejsze leczenie choroby Gravesa lekami tyreostatycznymi lub radiojodem nie wpływa na skuteczność leczenia immunosupresyjnego orbitopatii tarczycowej

An update on thyroid-associated ophthalmopathy in children and adolescents

Does thyroid surgery for Graves’ disease improve health-related quality of life?

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