“…In contrast, for the in-hospital mortality, reported in six studies [ 12 , 15 , 16 , 17 , 19 , 23 ], no statistically significant advantage was reported with either monotherapy (OR = 1.42, 95% CI [0.55, 3.70], p = 0.47), Figure 5 , with a significant heterogeneity observed (I 2 = 51%, p = 0.07). However, when reversing the heterogeneity via the sensitivity analysis, by excluding the study by Ku et al [ 15 ], a statistically reduced in-hospital mortality rate was observed in favour of the colistin monotherapy (OR = 2.27, 95% CI [1.24, 4.16], p = 0.008), with no heterogeneity (I 2 = 0%, p = 0.57), Figure S1.2 .…”