Time Course and Prognostic Value of Plasma Levels of N-Terminal Pro-Brain Natriuretic Peptide in Patients After Ischemic Stroke

Heart failure may be associated with the onset of ischemic stroke with atrial fibrillation

“…In the present study, plasma BNP level was elevated noticeably in the acute phase of stroke, and declined substantially thereafter, which is compatible with previous reports [5,[7][8][9]. To the best of our knowledge, no previous reports revealed serial change of plasma BNP level in stroke patients with AF.…”

“…In addition, plasma BNP levels have also been shown to be elevated in patients with acute ischemic stroke [5][6][7][8][9][10], in particular when accompanied with atrial fibrillation (AF) [5,7,10].…”

High pro-BNP levels predict the occurrence of atrial fibrillation after cryptogenic stroke

“…In addition, we did not investigate the temporal profile of pro-BNP, and some studies found that pro-BNP levels decrease in the days following a stroke. 23 In our study, we have found that pro-BNP levels $360 pg/mL determined during the acute phase of cryptogenic stroke may be useful to identify patients at risk of AF during the 2 years after the stroke. …”

Prognostic significance of admission levels of cardiac indicators in patients with acute ischaemic stroke: Prospective observational study

“…class 3, acute myocardial infarction and recurrent stroke or any cause of death as unfavourable outcomes. 28 The mechanistic basis for myoglobin elevations correlating with poor outcomes in patients with acute ischaemic stroke remains unclear, although there are a variety of plausible explanations. Central activation of the sympathetic nervous system in acute ischaemic stroke is known to have serious adverse effects on cardiac function and myocardial structure, 4,29 and to increase the release of myoglobin from injured myocardium, which may explain the propensity for adverse outcomes in patients with acute ischaemic stroke and increased myoglobin levels.…”