Abstract:SummaryTime related changes in distributions of body fluid volumes were studied in rats with either of two types of Goldblatt hypertension; two-kidney, one-clip (2K1C) and one-kidney, one-clip (1K1C) models. Plasma volume (PV), extracellular fluid volume (ECF), and total body water (TBW) were measured on days 1, 7, and 28 after renal artery stenosis. Mean arterial pressure (MAP) and plasma renin activity (PRA) were also determined in conscious rats.In the 2K1C rats each fluid compartment on any experimental da… Show more
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