According to the fundamental principles of high resolution sequence stratigraphy, this paper focused on the application of high resolution sequence stratigraphy to Silurian strata in Tazhong area. Based on the comprehensive study of logging, drilling and seismic information, the high resolution sequence boundaries of Silurian strata and two scales of datum level cycles (long-term and intermediate-term) can be recognized in Tazhong area. Seven chronstratigraphic boundaries can be recognized in Silurian strata, including four sequence boundaries, which were the transformation from datum level falling to datum level rising, and three flooding surfaces, which the transformation from datum level rising to datum level falling. The Silurian strata in Tazhong area can be divided into three third-order sequences which correspond to three long-term datum level cycles, and 11 fourth-order sequences (parasequence sets) relating to 11 intermediate-term datum level cycles. The classification aforementioned can much better solved the corresponding problem between the six lithological sections of Silurian strata and sequence formations, finally establishes the high resolution sequence stratigraphic framework of Silurian strata in Tazhong area.