The stabilization of cross-linked polyethylene (XLPE) cables is crucial to the safe working of power systems. In order to investigate the aging characteristics of cable insulation in the process of operation, 10 kV XLPE cables were electrically-thermally aged at an AC voltage of 26.1 kV and three temperatures: 103°C, 114°C, and 135°C. Cable samples at five aging stages were cut into slices and tested to determine their mechanical, physicochemical properties and dielectric strength. The changes in these properties were analyzed in terms of aging time. The mechanical strength and oxidation induction time have the same changing trend of decrease, because the chemical bonds of the cable insulation material are fractured when the XLPE cable is aged. The AC space charge presented a trend of gradual accumulation with aging time. The breakdown field strength after AC voltage application decreases monotonically with aging time, which could be a characteristic index to evaluate the degradation degree of the cable insulation. This research contributes to the comprehension of degradation mechanism and discovery of aging assessment criteria, which is of great significance in assessments of insulation properties and fault detection on power cables.