Abstract. The collisional coupling of relativistic electrons and non-relativistic ions in hot plasmas has been analysed. It is found that relativistic effects produce a new feature: while the condition T e < 3T i guarantees a stable collisional coupling between electrons and ions in low-temperature plasmas, relativistic effects shift the upper T e /T i boundary of stability to higher values. Moreover, for sufficiently high temperatures, T e,i > 75 keV, collisional decoupling between relativistic electrons and ions becomes impossible.