Time in range and HbA _1C after 6 months with a multidisciplinary program for children and adolescents with diabetes mellitus, real world data from Mexico City

Treatment Outcome and Associated Factors among Type 1 Diabetic Children<15 Years Admitted With DKA in Bahir Dar City Public Referral Hospital, North West, Ethiopia: A retrospective Cross Sectional Study

“…In spite of numerous advances in the management of type one diabetes mellitus, more than 70% of T1DM patients unable to maintain glycemic control (14).As a result, diabetic keto acidosis(DKA)became the most common sticky situation of T1DM in children with an incidence of 1-10% of diabetic clients per year in developed nations (7), (20).In countries such as Germany, Europe, north America and Australia the average rate of DKA ranges from 30 to 70% in the child diagnosed with T1DM (15), whereas, the proportion of DKA in Asian children among the total cohort was 33.6% (16).…”

Time to First Optimal Glycemic Control and its Predictors Among Type 1 Diabetic Children<15 Years in Bahir Dar City Public Referral Hospitals, North West Ethiopia: A Retrospective Follow Up Study

“…Diabetes mellitus pandemic have become one of the largest global health emergencies among non-communicable disease in this century (3). In many countries, over 500 000 children < 15 years old are diagnosed with T1DM(4, 6-8)with an average incidence of 3-4% per year worldwide(6, 7).This increment is also noted more alarmingly in developing countries (9,(10)(11)(12)(13)(14).…”

“…More over noncompliance rate escalating 50% that highlights the need for focusing on timely optimal glycemic control (10). Many children had also suffered from T1DM which is associated with high morbidity, mortality rate and most of the time the poor has been highly affecting by this disease (9,15,16).…”

“…A varieties of factors that predict glucose control in children with T1DM have documented (7,(18)(19)(20)(21)(22).High proportion of patients with uncontrolled glycemic level were due to sociodemographic factors, concomitant disease, personal and other clinical factors (16,17,23); health care system with limited resources, lack of trained health personnel and in ability of the patient or family to use and afford treatment expenditures (10,24). Uncontrolled glycemic situation results complication which can hurt many parts of the body including growth failure later in time (3,(22)(23)(24).…”

“…However, strict glycemic control minimizes the incidence and progression of such possible complication (14)(15)(16)(17).The Diabetes Control and Complication Trial (DCCT) and the follow-up study Epidemiology of Diabetes Interventions and Complications (EDIC) shows that, good glycemic control with in short duration delays the development of both acute and chronic complication in T1DM patients by 35-76% (9).Novel treatment are emerging to manage T1DM with the ultimate goal being to achieve glycemic control, limit weight gain, reduce comorbidities and improve quality of life (7).T1DM treatment is based on frequent monitoring of blood glucose and administration of insulin, in line with their meal and exercise (33)(34)(35).It was recommended that T1DM children should check their blood glucose at least four times a day(6).And which expected to bring 26.2% satisfactory glycemic control level (7,35).People with diabetes can live longer and have a healthy life if their diabetes is become aware of early and well-managed by multidisciplinary approach with the allocation of accessible resources (10,36,37).Being updated about the recent diabetes care can also help in improving rst glycemic control (15,38).…”