The application of quantitative interpretation techniques for hydrocarbon prospect evaluation from seismic has become so vital. The effective employment of these techniques is dependent on several factors: the quality of the seismic and well data, sparseness of data, the physics of rock, lithological and structural complexity of the field. This study adopts reflection pattern, amplitude versus offset (AVO), Biot–Gassmann fluid substitution and cross-plot models to understand the physics of the reservoir rocks in the field by examining the sensitivity of the basic rock properties; P-wave velocity, S-wave velocity and density, to variation in lithology and fluid types in the pore spaces of reservoirs. This is to ascertain the applicability of quantitative seismic interpretation techniques to explore hydrocarbon prospect in the studied field. The results of reflection pattern and AVO models revealed that the depth of interest is dominated by Class IV AVO sands with a high negative zero offset reflectivity that reduces with offset. The AVO intercept versus gradient plot indicated that both brine and hydrocarbon bearing sands can be discriminated on seismic. Fluid substitution modelling results revealed that the rock properties will favourably respond to variation in oil saturation, but as little as 5% gas presence will result in huge change in the rock properties, which will remain constant upon further increments of gas saturation, thereby making it difficult to differentiate between economical and sub-economical saturations of gas on seismic data. Rock physics cross-plot models revealed separate cluster points typical of shale presence, brine sands and hydrocarbon bearing sands. Thus, the response of the rock properties to the modelling processes adopted favours the application of quantitative interpretation techniques to evaluate hydrocarbon in the field.