Dengue fever is a mosquito-borne viral infection among the 20 prioritized Neglected Tropical Diseases recognised by the World Health Organization (WHO). Its incidence has increased globally and in India in the past two decades. Kerala, India, reported its first case of dengue fever in 1997, and the incidence has gradually increased since then, making dengue fever an endemic and serious health problem. This study is a descriptive study of the incidence and mortality of dengue fever in Kerala from its first report till the present. The study will use exploratory data analysis, time series analysis, and predictive analysis to understand the scale of dengue fever spread over time and near future.