High-precision time sequence forecasting is a complicated cyber-physical system (CPS) task. Due to the diversity of data scales and types, the classic time-series prediction model meets the challenge to deliver accurate prediction results for many forms of time-series data. This work proposes a hybrid model with long short-term memory (LSTM) and embedded empirical mode decomposition (EEMD) based on the entropy fusion feature. First, we apply EEMD in entropy fusion feature long short-term memory (ELSTM) to lessen pattern confusion and edge effects in traditional empirical mode decomposition (EMD). The sequence is then divided into intrinsic mode functions (IMF) by using EEMD. Then, feature vectors are constructed between IMFs and their respective information entropy for feature merging. LSTM is used to build a full connection network for each entropy fusion feature IMF subsequence for prediction and each type of IMF subsequence as the feature dimension to obtain its prediction results. Finally, the output results of all IMF subsequences are reconstructed to obtain the final prediction result. Compared with the LSTM method, the performance of the proposed method has been improved 64.33% on the evaluation metric MAPE. The proposed model has also delivered the best prediction outcomes across four different time-series datasets. The experimental results conclusively show that the proposed method outperforms other models compared.