Time series of tuberculosis mortality in Brazil (1980-2001)

Hino, Paula; Costa-Júnior, Moacyr Lobo da; Sassaki, Cinthia Midori; Oliveira, Mayra Fernanda de; Villa, Tereza Cristina Scatena; Santos, Cláudia Benedita dos

doi:10.1590/s0104-11692007000500009

Cited by 11 publications

(10 citation statements)

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“…Whereas the former had a cure rate of 71%, the latter had a cure rate of only 50%, which means that patients with tuberculosis-HIV co-infection had a 48% lower chance of cure than did HIV-negative patients. This relationship has been reported in other studies 29 , 30 and is related to the immunodeficiency caused by HIV in such patients, the time from diagnosis to treatment initiation, and the limited access to health care 31 . Even after the launch of the PNCT and after the establishment of the WHO and the Brazilian MS goal of curing 85% of reported cases by 2015, Brazil has not yet achieved this purpose, as shown by our analysis of the 2002-2012 period 1 …”

Section: Discussionsupporting

confidence: 68%

Temporal analysis of reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012

Gaspar¹,

Nunes

et al. 2016

J. bras. pneumol.

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Objective: To investigate the reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012. Methods: This was an observational study based on secondary time series data collected from the Brazilian Case Registry Database for the 2002-2012 period. The incidence of tuberculosis was stratified by gender, age group, geographical region, and outcome, as was that of tuberculosis-HIV co-infection. Results: Nationally, the incidence of tuberculosis declined by 18%, whereas that of tuberculosis-HIV co-infection increased by 3.8%. There was an overall decrease in the incidence of tuberculosis, despite a significant increase in that of tuberculosis-HIV co-infection in women. The incidence of tuberculosis decreased only in the 0-to 9-year age bracket, remaining stable or increasing in the other age groups. The incidence of tuberculosis-HIV co-infection increased by 209% in the ≥ 60-year age bracket. The incidence of tuberculosis decreased in all geographical regions except the south, whereas that of tuberculosis-HIV co-infection increased by over 150% in the north and northeast. Regarding the outcomes, patients with tuberculosis-HIV coinfection, in comparison with patients infected with tuberculosis only, had a 48% lower chance of cure, a 50% greater risk of treatment nonadherence, and a 94% greater risk of death from tuberculosis. Conclusions: Our study shows that tuberculosis continues to be a relevant public health issue in Brazil, because the goals for the control and cure of the disease have yet to be achieved. In addition, the sharp increase in the incidence of tuberculosis-HIV co-infection in women, in the elderly, and in the northern/northeastern region reveals that the population of HIV-infected individuals is rapidly becoming more female, older, and more impoverished.

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Section: Discussionsupporting

confidence: 68%

Temporal analysis of reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012

Gaspar¹,

Nunes

et al. 2016

J. bras. pneumol.

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“…TB mortality rates in Brazil seemed to be higher i.e. 5.9 per 100,000 in 1980 and 3.1 per 100,000 in 2001 [13]. Differences in the quality of the health care system, public health interventions and the socio economic situation of the population can explain the observed differences in TB death rates and their decline.…”

Section: Discussionmentioning

confidence: 99%

Will the European Union reach the United Nations Millennium declaration target of a 50% reduction of tuberculosis mortality between 1990 and 2015?

2017

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BackgroundThe Millennium Development Goals (MDG) provide targets for 2015. MDG 6 includes a target to reduce the tuberculosis (TB) death rate by 50% compared with 1990. We aimed to assess whether this target was reached by the European Union (EU) and European Economic Area countries.MethodsWe used Eurostat causes of death data to assess whether the target was reached in the EU. We calculated the reduction in reported and adjusted death rates and the annual average percentage decline based on the available data.ResultsBetween 1999 and 2014, the TB death rate decreased by 50%, the adjusted death rate by 56% and the annual average percentage decline was 5.43% (95% confidence interval 4.94–6.74) for the EU. Twenty of 26 countries reporting >5 TB deaths in the first reporting year reached the target of 50% reduction in adjusted death rate.ConclusionsThe EU reached the MDG target of a 50% reduction of the TB death rate and also the annual average percentage decline was larger than the 2.73% needed to reach the target. The World Health Organization ‘End TB Strategy’ requires a further reduction of the number of TB deaths of 35% by 2020 compared to 2015, which will challenge TB prevention and care services in the EU.

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“…A apresentação clínica da TB em idosos é variável 14 , afasta-se dos sintomas clássicos e apresenta, sobretudo, sintomas não característicos, como: anorexia, fraqueza, perda de peso e alteração mental 14,15 . Isso implica frequentemente o retardo do diagnóstico pela dificuldade de reconhecimento do quadro clínico, que, muitas vezes, é confundido com alterações próprias do envelhecimento, por profissionais de saúde e pelos familiares, ou não é referido de forma adequada pelo próprio paciente 7,14,16,17 .…”

Section: Revisão E Literaturaunclassified

Tuberculose em pessoas idosas: porta de entrada do sistema de saúde e o diagnóstico tardio [Tuberculosis among the elderly: health care system gateway and late diagnosis]

et al. 2016

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RESUMO Objetivo: analisar os fatores relacionados ao retardo do diagnóstico da tuberculose (TB) em idosos em um dos municípios da região metropolitana de João Pessoa/Paraíba-Brasil, avaliando-os sob a dimensão porta de entrada. Método: pesquisa qualitativa, com participação de sete pessoas idosas. Os relatos foram coletados mediante entrevista e submetidos à análise de conteúdo em 2010 e 2011. Estudo aprovado pelo Comitê de Ética e Pesquisa, no. 0589/2008. Resultados: atenção básica em saúde (ABS) não se configurou como principal porta de entrada dos idosos para o diagnóstico da tuberculose no município estudado, revelando que sua organização apresenta fragilidades referentes às ações de saúde, ao acesso e ao vínculo, que interferem na sua busca como porta de entrada. Conclusão: exige-se uma nova lógica do processo de trabalho em que as práticas de saúde priorizem tecnologias que potencializem acolhimento e vínculo, de modo que seja abreviada a confirmação diagnóstica e o início do tratamento da TB. Palavras-chave: Atenção primária à saúde; programa saúde da família; saúde do idoso; tuberculose.

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Time series of tuberculosis mortality in Brazil (1980-2001)

Cited by 11 publications

References 13 publications

Temporal analysis of reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012

Temporal analysis of reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012

Will the European Union reach the United Nations Millennium declaration target of a 50% reduction of tuberculosis mortality between 1990 and 2015?

Tuberculose em pessoas idosas: porta de entrada do sistema de saúde e o diagnóstico tardio [Tuberculosis among the elderly: health care system gateway and late diagnosis]

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