Time to Depression Treatment in Primary Care Among HIV-infected and Uninfected Veterans

Hooshyar, Dina; Goulet, Joseph L.; Chwastiak, Lydia; Crystal, Steven; Gibert, Cynthia L.; Mattocks, Kristin M.; Rimland, David; Rodriguez‐Barradas, Maria C.; Justice, Amy C.

doi:10.1007/s11606-010-1323-z

Cited by 11 publications

(5 citation statements)

References 33 publications

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“…5,14 Pertinent to the issues of universal access, coordinated care, and increased usage of electronic medical record systems promoted by the Obama Administration are two reports in this issue of JGIM. uninfected patients enrolled in the Veterans Aging Cohort Study (VACS) 15 confirms our prior understanding that severely depressed patients are more likely to be recognized and treated for this condition than less severely affected individuals. It also extends our knowledge to an HIV-infected population receiving care within a single-payer system where clinicians make extensive use of a sophisticated electronic medical record system.…”

supporting

confidence: 61%

Moving Medical Advances from Prototype into Practice

Rollman

2010

J GEN INTERN MED

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supporting

confidence: 61%

Moving Medical Advances from Prototype into Practice

Rollman

2010

J GEN INTERN MED

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“…Depression is common in persons living with chronic disease including HIV and is associated with several adverse outcomes including medication nonadherence, impaired functional status, neurocognitive impairment, and mortality [ 33 , 174 – 180 ]. Clinicians do have well established brief screening instruments for depression available to them that can be utilized repeatedly for assessment [ 181 – 183 ]. Neurocognitive assessment generally includes an evaluation for depression since cognitive impairment is common with this disorder and may be improved with therapeutic interventions including treatment with antiretroviral therapy [ 177 ].…”

Section: Physical Comorbidities Effecting Cognitionmentioning

confidence: 99%

HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities

Tedaldi

Minniti

Fischer

2015

BioMed Research International

115

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The prevalence of HIV (human immunodeficiency virus) associated neurocognitive disorders (HAND) will undoubtedly increase with the improved longevity of HIV-infected persons. HIV infection, itself, as well as multiple physiologic and psychosocial factors can contribute to cognitive impairment and neurologic complications. These comorbidities confound the diagnosis, assessment, and interventions for neurocognitive disorders. In this review, we discuss the role of several key comorbid factors that may contribute significantly to the development and progression of HIV-related neurocognitive impairment, as well as the current status of diagnostic strategies aimed at identifying HIV-infected individuals with impaired cognition and future research priorities and challenges.

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“…29 Fortunately, treatment of depression pharmacologically or through other behavioral interventions can be beneficial with demonstrated improved clinical outcomes and HAART adherence; 12,[31][32][33][34][35][36] however, differential use of antidepressants has been documented. [37][38][39] The relationship of depression and its treatment and HAART adherence is a dynamic one and longitudinal evaluations of HIV-infected persons in the evolving chronic disease model of care are needed. Assessing depression in HIV-infected persons can be done through structured interviews or standardized screening instruments that may be selfadministered or done electronically.…”

mentioning

confidence: 99%

Sadness in the SUN: Using Computerized Screening to Analyze Correlates of Depression and Adherence in HIV-Infected Adults in the United States

Tedaldi

Berg-Wolf

Richardson

et al. 2012

AIDS Patient Care and STDs

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We used a standardized screening tool to examine frequency of depression and its relation to antiretroviral medication adherence among HIV-infected persons on highly active antiretroviral therapy (HAART) in the Study to Understand the Natural History of HIV/AIDS in the Era of Effective Therapy (SUN Study). This is a prospective observational cohort of 700 HIV-infected patients enrolled between March 2004 and June 2006 in four U.S. cities, who completed a confidential audio computer-assisted self-interview [ACASI] with behavioral risk and health-related questions at baseline and 6-month follow-up visits, including the nine-question PRIME-MD depression screener and a validated 3-day antiretroviral adherence question. Among 539 eligible participants receiving HAART, 14% had depression at baseline (22% women, 12% men). In multivariable analysis using generalized estimating equations (GEE) to account for repeated measurements through 24 months of follow-up, persons who reported depression on a given ACASI were twice as likely to report nonadherence to antiretrovirals on the same ACASI (Odds ratio [OR] 2.02, 95% CI: 1.15, 3.57] for mild/moderate depression versus none); such persons were also less likely to have HIV viral load < 400 copies/mL. Self-administered computerized standardized screening tools can identify at-risk individuals with depression who may benefit from interventions to improve antiretroviral adherence.

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Time to Depression Treatment in Primary Care Among HIV-infected and Uninfected Veterans

Cited by 11 publications

References 33 publications

Moving Medical Advances from Prototype into Practice

Moving Medical Advances from Prototype into Practice

HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities

Sadness in the SUN: Using Computerized Screening to Analyze Correlates of Depression and Adherence in HIV-Infected Adults in the United States

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