Time to Rehospitalization in Patients With Major Depressive Disorder Taking Venlafaxine or Fluoxetine

Risk of New Onset Type Ii Dm in MDD Patients Receiving Second-Generation Antipsychotics Treatment: A Nationwide Cohort Study

“…Hospitalization is known to be an adverse event of severe psychopathology; the main reasons why MDD patients receive inpatient treatment are because of suicidal crises, disease progression, and function deterioration. [26,51] Although the study results may not be generalized to all patients with MDD, the results add to our knowledge of the association between DM risk and clinical variables in a subpopulation with more severe psychopathology. In addition, new onset patients whose initial psychiatric hospitalizations occurred in the most recent years (2008-2012) were not available for our study.…”

Changes in healthcare resource use and costs associated with early versus delayed initiation of atypical antipsychotic adjunctive treatment in major depressive disorder

“…The decreased rates of hospitalization and ED visits associated with AAP use are not unexpected, and in particular among patients with MDD, as these events have been shown to be related to suicidal crisis, disease progression, relapse, and functional deterioration 36,37 . Patients with depression have a higher risk of hospital admission for non-psychiatric conditions than others 38 .…”

Management of bipolar depression with lamotrigine: an antiepileptic mood stabilizer

“…Treatment of bipolar II depression with adjunctive lamotrigine may also be associated with a history of suicide-attempts and a number of depression-related prior hospitalization in case of poor response to the adjunctive lamotrigine therapy, as per the data from the 52-week follow-up study. In case of a history of previous hospitalization, an increased risk of re hospitalization, treatment resistance, and depressive relapse was reported ( Souery et al, 2007 ; Lin et al, 2008 ). The risk of bipolar disorder may be well influenced by harm avoidance linked to genetic variations, which can also alter responses to the pharmacological treatment ( Mandelli et al, 2009 ).…”