1998
DOI: 10.1016/s0168-8278(98)80262-6
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Time trends and age-period-cohort effects on the incidence of primary liver cancer in a well-defined French population: 1976–1995

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Cited by 52 publications
(28 citation statements)
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“…In British narrative reviews of HCC, it is commonly asserted that around 80% of tumours develop in cirrhotic livers. [71][72][73] This figure is in line with the results of a few small UK series from the 1980s, in which rates of 73-80% were reported, [74][75][76] and comparable with data from elsewhere in Europe (71-88% in France, [77][78][79][80] 75-90% in Germany, [81][82][83][84][85] 77-97% in Italy [86][87][88][89][90][91][92] and 93% in Spain 93 ). The picture may be different in North America, where similar studies suggest that the proportion of HCC patients who have cirrhosis is as low as 58% 94 to 63%.…”
Section: Aetiologysupporting
confidence: 84%
“…In British narrative reviews of HCC, it is commonly asserted that around 80% of tumours develop in cirrhotic livers. [71][72][73] This figure is in line with the results of a few small UK series from the 1980s, in which rates of 73-80% were reported, [74][75][76] and comparable with data from elsewhere in Europe (71-88% in France, [77][78][79][80] 75-90% in Germany, [81][82][83][84][85] 77-97% in Italy [86][87][88][89][90][91][92] and 93% in Spain 93 ). The picture may be different in North America, where similar studies suggest that the proportion of HCC patients who have cirrhosis is as low as 58% 94 to 63%.…”
Section: Aetiologysupporting
confidence: 84%
“…Trends for an increase in HCC-related deaths are looming on the horizon in many countries worldwide (table 3) [7][8][9][10][11][12], albeit the number of death per 100,000 population is still much smaller than what we now have in Japan. High prevalence rates of HCC in males Ͼ65 years reported from Scotland breathtakingly resemble what happened in Japan with its sequelae [13].…”
Section: Projection Of What Has Happened and Whatmentioning
confidence: 99%
“…in the usa, the age-adjusted incidence rates tripled between 1975 and 2005, 2 while in France, the incidence in men increased from 7.5 per 100,000 for the period 1976-1979 to 10.2 per 100,000 for the period 1992-1995. 3 But over the past decade some favorable trends toward stabilization have been observed in France and italy, particularly in women and young adults. 4 more than 80% of cases of HCC develop in patients with pre-existing cirrhosis, which is mainly caused by hepatitis B in africa and asia, hepatitis C in Japan, southern europe and the usa, and alcohol in europe and north america.…”
Section: Introductionmentioning
confidence: 99%