2017
DOI: 10.1111/liv.13340
|View full text |Cite
|
Sign up to set email alerts
|

Time‐trends in incidence and prognosis of hepatocellular carcinoma in Denmark: A nationwide register‐based cohort study

Abstract: HCC incidence increased between 2007 and 2011. Concurrently, the HCC stage at diagnosis and patient survival improved. The likely reasons for the changes include easier access to HCC workup, changing diagnostic criteria for HCC, increased prevalence of risk factors for HCC, and improved treatment of patients with HCC.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

1
25
0

Year Published

2017
2017
2024
2024

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 23 publications
(26 citation statements)
references
References 37 publications
1
25
0
Order By: Relevance
“…A key characteristic in the Norwegian population has been the relatively high percentage of HCC patients without liver cirrhosis, recently reported to be 44% (34). Even the HCC populations in the Nordic countries seem to differ somewhat as the rate of non-cirrhotic HCC reported from Denmark and Sweden is 20% and 35% (35,36), respectively. HCC receive the majority of the blood supply from the hepatic arterial system (37).…”
Section: Primary Liver Cancer -Hepatocellular Carcinomamentioning
confidence: 99%
“…A key characteristic in the Norwegian population has been the relatively high percentage of HCC patients without liver cirrhosis, recently reported to be 44% (34). Even the HCC populations in the Nordic countries seem to differ somewhat as the rate of non-cirrhotic HCC reported from Denmark and Sweden is 20% and 35% (35,36), respectively. HCC receive the majority of the blood supply from the hepatic arterial system (37).…”
Section: Primary Liver Cancer -Hepatocellular Carcinomamentioning
confidence: 99%
“…Hepatocellular carcinoma (HCC) is one of the commonest malignant tumors and a leading cause of cancer-related death [ 1 , 2 ]. With improvements in surgical techniques, perioperative management, liver transplantation and adjuvant treatment, the 5-year survival rate for HCC has somewhat increased [ 3 5 ]. However, the risks of recurrence and intrahepatic or extrahepatic metastasis after surgery remain high [ 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…1,2 HCC may also develop in a noncirrhotic setting, such as chronic hepatitis B, chronic hepatitis C with advanced fibrosis, and nonalcoholic fatty liver, 3 although less frequently. According to community-based cancer registries, the 5-year survival rate of primary liver cancer is approximately 15% 4,5 ; this high mortality rate is mainly due to late detection in many patients and a high recurrence rate after curative treatment. Therefore, all patients having an HCC risk high enough to consider surveillance cost-effective or those radically treated should be kept on regular surveillance for early detection of this tumor or its recurrence.…”
mentioning
confidence: 99%