Time trends of cancer incidence in Setif, Algeria, 1986–2010: an observational study

Abstract

Background: Incidence rates of various cancers are increasing in Arab countries and are expected to reach those of industrialized ones in few decades. This paper aimed to describe the incidence rates of most common cancers -and/or of those cancer preventable through modifiable behaviors -recorded in the province of Setif, Algeria from 1986 through 2010. Methods: Cancer diagnoses for the 1986-2010 period were provided by the population-based Cancer Registry of Setif, disentangled by site, morphology, age (quinquennia), sex, and calendar period. The corresponding population was obtained from the Algerian Institute of Statistics. Age-standardized rates (world population) (ASR-WR) were computed by calendar period (five quinquennias from 1986-1990 to 2006-2010), while annual percent changes (APCs) were computed for the period 1996-2010. Results: During the 2006-2010 period, ASR-WR for all cancer sites were 106.4/100,000 in men and 110.3 in women. The four leading cancers were: lung (18.0%); colon-rectum (9.6%); bladder (9.1%); and prostate (6.5%) in men; breast (36.4%); colon-rectum (8.5%); cervix uteri (6.0%); and thyroid (6.0%) in women. Between 1996-2010, overall cancer incidence increased statistically significantly (p < 0.05) in both men (APC = +2.5%) and women (APC = +3.7%). Statistically significant decreasing trends were observed for nasopharyngeal carcinoma (APC = −3.4%) in men, and for cervical (APC = −4.2%) and gallbladder (APC = −3.2%) cancers in women. Statistically significant increasing trends were observed for most common cancers both in men (lung:+1.8%, colon-rectum:+5.4%, prostate:+4.3%, liver:+8.9%, and bladder:+5.9%) and women (breast:+8.2%, colon-rectum:+4.5%, lung:+10.0%, liver:+5.4%, thyroid:+5.3%, and larynx:+13.8%). Conclusions: International recommendations against cancer must be strongly promoted in Setif after taking into account epidemiological transition, lifestyle, and environmental changes.

Polymorphic Deletions of Glutathione S-Transferases M1, T1 and Bladder Cancer Risk in Algerian Population

“…This difference in incidence is greater than those reported in previous studies among North Africans [3] and Algerian population [4]. We have also shown that cigarette smoking was a significant risk factor for bladder cancer risk (OR=3.55; CI: 2.9-5.48; p=1.21E-08).…”

“…Between 2006 and 2010, the incidence for Algerian men were 10.3/100,000 person-years, this represents 9.1% of the global cancer incidence in Algeria [4].…”

“…The risk of this disease increases with advancing age and most cases are diagnosed above 65 years of age [6]. The incidence is 5-7 times higher in males than in females in Algeria and North Africa [3,4].…”

Colorectal cancer incidence and clinicopathological features in northern Tunisia 2007–2009

“…The present study showed that 60 years was the mean age at diagnosis in northern Tunisia that is slightly higher than that observed in other north-African countries such as Morocco and Algeria with an average age around 55 years [37][38][39][40]. The average age is much lower in Egypt and some African countries with, respectively, 50 and 47 years [31,[41][42][43].…”

Patterns of Benign and Malignant Lesions of the Thyroid in Two Wilayahs of Northeastern Algeria

“…8 (1993–1997) [15] and from cancer registry reports for years 2003, 2006, and 2007 [16–18]. Time trends of cancer incidence in Setif, Algeria, 1986–2010 were recently reported [19] and additional data were obtained from CIV Vol. 6 (1986–1989) [13], Vol.…”