Calderas are among the most active and dangerous volcanoes. Caldera unrest is defined by enhanced seismicity, gravity changes, surface deformation, and degassing. Although much caldera unrest does not lead to an eruption, every eruption is preceded by an unrest episode. Therefore, the proper description of unrest and the forecast of its possible outcome is a timely and challenging task. Here we review the best known unrest at calderas from 1988 to 2014, building on previous work and proposing an updated database. Where established, the root cause for unrest is always magmatic; none was purely hydrothermal or tectonic. An interpretive classification of unrest invokes two spectra-compositional (mafic to felsic) and the state of magma conduits feeding from the magma reservoir(s) to the surface (from fully plugged, through semiplugged, to open). Magma and gas in open conduits can rise and erupt freely; magma in semiplugged conduits erupts less frequently yet still allows some gas to escape; plugged conduits allow neither magma nor gas to escape. Unrest in mafic calderas is subtler, less pronounced, and repeated, especially with open systems, ensuring the continuous, aseismic, and moderate release of magma. Plugged felsic calderas erupt infrequently, anticipated by isolated, short and seismically active unrest. Semiplugged felsic calderas also erupt infrequently and are restless over decades or centuries, with uplift, seismicity, and degassing and, on the longer-term, resurgence, suggesting repeated stalled intrusions. Finally, the expected advances in better understanding caldera unrest are discussed.