Timing and Duration of Myocardial Ischemia on Holter Monitoring Following Percutaneous Coronary Intervention and Their Association With Clinical Outcomes (a PROTECT-TIMI 30 Substudy Analysis)

Gibson, C. Michael; Pride, Yuri B.; Buros, Jacqueline L.; Ciaglo, Lauren N.; Morrow, David A.; Scirica, Benjamin M.; Stone, Peter H.

doi:10.1016/j.amjcard.2009.02.044

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…In one study, after multivariable adjustment, only ST-segment depression during AECG monitoring, and not ST-segment depression during exercise testing, significantly predicted worse outcomes (Rocco et al, 1988). In patients with unstable coronary syndromes, silent ischemia can predict both short-term and long-term risk (Gibson et al, 2009;Gottlieb, Weisfeldt, Ouyang, Mellits, & Gerstenblith, 1987;Langer, Singh, Freeman, Tibshirani, & Armstrong, 1995;Patel et al, 1997;Scirica et al, 2009).…”

Section: Chest Pain and Coronary Ischemiamentioning

confidence: 99%

2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry

et al. 2017

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Ambulatory ECG (AECG) is very commonly employed in a variety of clinical contexts to detect cardiac arrhythmias and/or arrhythmia patterns which are not readily obtained from the standard ECG. Accurate and timely characterization of arrhythmias is crucial to direct therapies that can have an important impact on diagnosis, prognosis or patient symptom status. The rhythm information derived from the large variety of AECG recording systems can often lead to appropriate and patient-specific medical and interventional management. The details in this document provide background and framework from which to apply AECG techniques in clinical practice, as well as clinical research.

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Section: Chest Pain and Coronary Ischemiamentioning

confidence: 99%

2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry

et al. 2017

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“…The rationale for developing additional potent antithrombotic drugs was underscored by an analysis that demonstrated a 5-fold increase in death or MI in patients with NSTE-ACS who were treated with contemporary intensive antithrombotic regimens who had ischemia on continuous electrocardiographic monitoring in the first 48 h after PCI compared with those who did not (82).…”

Section: Figure 2 Main Findings Of the Plato Trialmentioning

confidence: 99%

The Year in Non–ST-Segment Elevation Acute Coronary Syndrome

Giugliano

Braunwald

2010

Journal of the American College of Cardiology

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“…[37] The presence of silent ischemia in these patients can provide important prediction of both short-term and long-term risk (Figure 5). [37-41] In patients presenting with unstable angina who were managed medically, evidence of silent ischemia during 48 hours of continuous ECG monitoring was predictive of poor outcomes at both 1-month and 2-years. [42] In a more modern cohort of patients enrolled in the Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome—Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) trial, most of whom underwent PCI, recurrent ischemia on cECG portended a poor prognosis and was strongly and independently associated with poor cardiovascular outcomes, including cardiovascular death (Figure 6).…”

Section: Introductionmentioning

confidence: 99%

The Clinical Significance of Continuous ECG (Ambulatory ECG or Holter) Monitoring of the ST-Segment to Evaluate Ischemia: A Review

Wimmer¹,

Scirica²,

Stone³

2013

Progress in Cardiovascular Diseases

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Silent ischemia is a common manifestation of coronary artery disease (CAD). Continuous ECG (cECG) monitoring is an effective tool for assessing the frequency and duration of silent ischemic episodes for patients with CAD and for risk stratifying asymptomatic patients or those after an acute coronary syndrome by identifying those at increased risk for future cardiovascular events or death. cECG also allows monitoring of the effectiveness of therapy in patients with CAD. Treatment strategies targeted toward the elimination of silent ischemia have shown that revascularization was better than medical therapy in eliminating silent ischemia, but large scale, prospective studies targeting silent ischemia as a treatment endpoint are still lacking. Future research is warranted to study the effects of newer medical agents or the selected use of revascularization in those patients with persistent silent ischemia despite current medical regiments.

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Timing and Duration of Myocardial Ischemia on Holter Monitoring Following Percutaneous Coronary Intervention and Their Association With Clinical Outcomes (a PROTECT-TIMI 30 Substudy Analysis)

Cited by 4 publications

References 19 publications

2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry

2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry

The Year in Non–ST-Segment Elevation Acute Coronary Syndrome

The Clinical Significance of Continuous ECG (Ambulatory ECG or Holter) Monitoring of the ST-Segment to Evaluate Ischemia: A Review

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