Timing-Dependent Effects of Transcranial Direct Current Stimulation on Hand Motor Function in Healthy Individuals: A Randomized Controlled Study

Jo, Nam-Gyu; Kim, Gi-Wook; Won, Yu Hui; Park, Sung-Hee; Seo, Jeong-Hwan; Ko, Myoung-Hwan

doi:10.3390/brainsci11101325

Cited by 5 publications

(1 citation statement)

References 51 publications

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“…The Finger Tapping Test (FTT) was performed for assessment of manual motor skills. This test has been used for many years in the neuropsychological assessment of brain damage, being an indicator of cortical activity [13], as well as being used in NIBS studies as a measure of manual dexterity [14]. The Tapping Pro version 1.0.8.1 mobile application was used to perform this test, as it provided, in addition to the number of taps per unit of time, graphs that allowed obtaining the explosive velocity (number of taps in the first 5 seconds).…”

Section: Outcome Measuresmentioning

confidence: 99%

Manual Dexterity and Hand Grip Strength Modifications After Application of Transcranial Static Magnetic Field Stimulation (tSMS) Over the Primary Motor Cortex (M1) in Healthy Subjects: A Triple-Blind, Randomized Clinical Trial

Navarro-López,

Carratalá-Tejada,

Oliviero

et al. 2024

Preprint

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: Objective. To test the hypothesis that a session of unilateral tSMS over the dominant primary motor cortex (M1) in healthy subjects produces a transient decrease in manual dexterity. Methods. A triple-blinded randomized control trial was conducted in 40 healthy participants who were allocated to real- or sham-tSMS group. Each participant underwent one session of tSMS and were assessed before, immediately after, 15 minutes, and 40 minutes after stimulation. Outcome measures were Finger Tapping Test (FTT), 5-seconds FTT, nine Hole Peg Test, and the hand grip assessment. Results: Significant differences were found between groups 15 minutes after stimulation in favor of the tSMS group in the FTT (2.2 ± 0.99; CI= .18-4.22; d= .84p=.034), and 5-second FTT (4.2 ± 1.98; CI= .199-8.2, d= .68; p=.04). In the intragroup analysis, a significantly lower number of taps 15 minutes after stimulation was observed in sham group (3.3 ± 1.01; CI= .47-6.13; d= .42; p=.015), but not in the real stimulation group. Conclusion: A unilateral session of tSMS in the M1 of the dominant hemisphere of healthy individuals does not reduce manual dexterity or grip strength. This technique could have benefits on the motor performance of the arm contralateral to the stimulated motor cortex

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Section: Outcome Measuresmentioning

confidence: 99%

Manual Dexterity and Hand Grip Strength Modifications After Application of Transcranial Static Magnetic Field Stimulation (tSMS) Over the Primary Motor Cortex (M1) in Healthy Subjects: A Triple-Blind, Randomized Clinical Trial

Navarro-López,

Carratalá-Tejada,

Oliviero

et al. 2024

Preprint

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Short-term ocular dominance plasticity is not modulated by visual cortex tDCS but increases with length of monocular deprivation

Chen

Bobier

Thompson

2023

Sci Rep

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Transcranial direct current stimulation (tDCS) of the occipital lobe may modulate visual cortex neuroplasticity. We assessed the acute effect of visual cortex anodal (a-)tDCS on ocular dominance plasticity induced by short-term monocular deprivation (MD), a well-established technique for inducing homeostatic plasticity in the visual system. In Experiment 1, active or sham visual cortex tDCS was applied during the last 20 min of 2-h MD following a within-subjects design (n = 17). Ocular dominance was measured using two computerized tests. The magnitude of ocular dominance plasticity was unaffected by a-tDCS. In Experiment 2 (n = 9), we investigated whether a ceiling effect of MD was masking the effect of active tDCS. We replicated Experiment 1 but used only 30 min of MD. The magnitude of ocular dominance plasticity was decreased with the shorter intervention, but there was still no effect of active a-tDCS. Within the constraints of our experimental design and a-tDCS parameters, visual cortex a-tDCS did not modulate the homeostatic mechanisms that drive ocular dominance plasticity in participants with normal binocular vision.

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Anodal tDCS improves neuromuscular adaptations to short-term resistance training of the knee extensors in healthy individuals

Angius,

Ansdell,

Škarabot

et al. 2024

Journal of Neurophysiology

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Experimental studies showed improvement in physical performance following acute application of transcranial direct current stimulation (tDCS). This study examined the neuromuscular and neural response to a single training session (Part 1) and after a 3-week resistance training (Part 2) performed with the knee extensors, preceded by tDCS over the primary motor cortex. Twenty-four participants (age, 30 ± 7 years; stature, 172 ± 8 cm; mass, 72 ± 15 kg) were randomly allocated to perform either resistance training with anodal tDCS (a-tDCS), or by a placebo tDCS (Sham). Resistance training consisted of 3 × 10 isometric contractions of 3 s at 75% MVC. Measures of neuromuscular function (MVC, voluntary activation and potentiated twitch force), corticospinal excitability, and short and long cortical inhibition were assessed. Acute tDCS did not affect neuromuscular and neural responses to a single training session (all ps ≥ 0.10). Conversely, after the 3-week training program, MVC increased in both groups ( p < 0.01), with a greater increase observed for a-tDCS vs. Sham (⁓6%, p = 0.04). Additionally, increased voluntary activation (⁓2%, p = 0.04) and corticospinal excitability (⁓22%, p = 0.04), accompanied with shorter silent period (-13%, p = 0.04) was found following a-tDCS vs. Sham. The potentiated twitch force and measures of short and long cortical inhibition did not change after training programme (all ps ≥ 0.29). Pre-training administration of tDCS only resulted in greater neuromuscular adaptations following 3-weeks of resistance training. These results provide new evidence that tDCS facilitates adaptations to resistance training in healthy individuals.

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Timing-Dependent Effects of Transcranial Direct Current Stimulation on Hand Motor Function in Healthy Individuals: A Randomized Controlled Study

Cited by 5 publications

References 51 publications

Manual Dexterity and Hand Grip Strength Modifications After Application of Transcranial Static Magnetic Field Stimulation (tSMS) Over the Primary Motor Cortex (M1) in Healthy Subjects: A Triple-Blind, Randomized Clinical Trial

Manual Dexterity and Hand Grip Strength Modifications After Application of Transcranial Static Magnetic Field Stimulation (tSMS) Over the Primary Motor Cortex (M1) in Healthy Subjects: A Triple-Blind, Randomized Clinical Trial

Short-term ocular dominance plasticity is not modulated by visual cortex tDCS but increases with length of monocular deprivation

Anodal tDCS improves neuromuscular adaptations to short-term resistance training of the knee extensors in healthy individuals

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