Tin(IV) Schiff base complexes: Synthesis, thermodynamic and anti bacterial investigation, experimental and theoretical studies

Abstract

A series of five coordinated diorganotin(IV) unsymmetrical Schiff base complexes have been synthesized. The structure determination and characterization of these complexes were made on the basis of UV-Vis, IR, (1 H and 119 Sn) NMR spectroscopy as well as elemental analysis. The binding site of the ligand was identified by IR spectroscopic measurement. Computational analyses at the level of DFT were performed to study its electronic and molecular structures. The molecular geometry, infrared vibrational frequencies, HOMO-LUMO energy gap, dipole moment, Mulliken charges, HF energies were calculated. The theoretical results were consistent with the experimental data reported. The Schiff base ligands and synthesized tin(IV) complexes were screened for their in vitro growth inhibiting activity against different strains of bacteria. Results indicated that the complexes exhibited good antibacterial activities than the ligands. Also the thermodynamic formation constants of the Schiff bases as donors with Me2SnCl2 as an acceptor were measured using UV-Vis spectrophotometric titration for 1:1 complex formation at constant ionic strength (I = 0.1 M NaClO4) and at 25 ºC.

Synthesis, characterization and antibacterial studies of ciprofloxaci-imines and their complexes with oxozirconium(IV), dioxomolybdenum(VI), and dioxotungsten(VI)

“…The electronic spectra of H2L1 and H2L2 along compounds at 200-1100 nm are listed in Table 3. Notably, distinctive peaks emerge wavelengths at 37363-37735 cm -1 may be signified to (π→π*) transition and at 34982, 35211 cm -1 are assigned to (n→π*) transition in cip-imine [23]. Such transitions typically manifest in unsaturated hydrocarbons that incorporate ketone or azomethine groups [19].…”

Performance of Schiff Bases Metal Complexes and their Ligand in Biological Activity: A Review

“…Also, the calculation was included IR frequencies, HOMO, LUMO energy gap, dipole moment, Mulliken charges and Hartree-Fock energies. The bacteriological activity of Schiff base with all complexes were tested against Staphylococcus aureus and Escherichia coli by growth-inhibiting zone and was gave a good activity against these bacteria [37]. Figure 21.…”