Tinnitus and Sucide

Lewis, John E.; Stephens, S. D. G.; McKenna, Laurence

doi:10.1111/j.1365-2273.1994.tb01147.x

Cited by 103 publications

(76 citation statements)

References 8 publications

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“…Tinnitus can inflict a wide range of distress; it has been strongly correlated with difficulty sleeping, irritability, anxiety, and depression (Andersson, 2002(Andersson, , 2004Andersson and McKenna, 1998;Belli et al, 2008;Cronlein et al, 2007;Dobie, 2003;Erlandsson and Hallberg, 2000;Folmer and Griest, 2000;Folmer et al, 1999;Halford and Anderson, 1991;Hebert and Carrier, 2007;Marciano et al, 2003;McKenna, 2000;McKenna et al, 1991;Robinson et al, 2003;Tyler and Conrad-Armes, 1983;Tyler et al, 2007). Tinnitus has been shown to negatively influence cognitive functioning such as working memory and attention (Rossiter et al, 2006;Stevens et al, 2007), and at the extreme, has been linked to suicide ( Johnston and Walker, 1996;Lewis et al, 1994;Turner et al, 2007). Accompanied by these clinical sequelae, the cost for seeking clinical help has been staggering.…”

Section: Introductionmentioning

confidence: 99%

Blast-Induced Tinnitus and Hearing Loss in Rats: Behavioral and Imaging Assays

Mao

Pace

Pierozynski

et al. 2012

Journal of Neurotrauma

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The current study used a rat model to investigate the underlying mechanisms of blast-induced tinnitus, hearing loss, and associated traumatic brain injury (TBI). Seven rats were used to evaluate behavioral evidence of tinnitus and hearing loss, and TBI using magnetic resonance imaging following a single 10-msec blast at 14 psi or 194 dB sound pressure level (SPL). The results demonstrated that the blast exposure induced early onset of tinnitus and central hearing impairment at a broad frequency range. The induced tinnitus and central hearing impairment tended to shift towards high frequencies over time. Hearing threshold measured with auditory brainstem responses also showed an immediate elevation followed by recovery on day 14, coinciding with behaviorally-measured results. Diffusion tensor magnetic resonance imaging results demonstrated significant damage and compensatory plastic changes to certain auditory brain regions, with the majority of changes occurring in the inferior colliculus and medial geniculate body. No significant microstructural changes found in the corpus callosum indicates that the currently adopted blast exposure mainly exerts effects through the auditory pathways rather than through direct impact onto the brain parenchyma. The results showed that this animal model is appropriate for investigation of the mechanisms underlying blast-induced tinnitus, hearing loss, and related TBI. Continued investigation along these lines will help identify pathology with injury/recovery patterns, aiding development of effective treatment strategies.

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Section: Introductionmentioning

confidence: 99%

Blast-Induced Tinnitus and Hearing Loss in Rats: Behavioral and Imaging Assays

Mao

Pace

Pierozynski

et al. 2012

Journal of Neurotrauma

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“…15 É um transtorno que produz extremo desconforto, de difícil caracterização e tratamento, e de acordo com sua gravidade pode excluir os acometidos do convívio social e até levar ao suicídio. 5,7,8 Os zumbidos podem ser percebidos de várias formas e os achados quanto à sua medida são controversos. Por isso, nenhuma forma de medida padronizada foi incorporada à rotina audiológica.…”

Section: Introductionunclassified

Incômodo causado pelo zumbido medido pelo Questionário de Gravidade do Zumbido

2006

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OBJETIVO:O Tinnitus Handicap Inventory é um questionário para avaliar as conseqüências do zumbido, quantificando os déficits psicoemocionais e funcionais provocados pelo sintoma. O objetivo do estudo foi apresentar e testar a adaptação para o português brasileiro desse questionário, denominado Questionário de Gravidade do Zumbido. MÉTODOS:O questionário traduzido foi aplicado em 135 indivíduos com queixa de zumbido atendidos em dois ambulatórios de audiologia da cidade de Bauru, SP, encaminhados para avaliação audiológica. A consistência interna foi avaliada pelos coeficientes α de Cronbach, comparados aos obtidos para a versão original. RESULTADOS:Obteve-se boa confiabilidade tanto para as escalas (0,76<α<0,85) quanto para todo o questionário, visto que o valor obtido (α=0,93) é idêntico àquele encontrado na consistência total do instrumento original. CONCLUSÕES:Os resultados sugerem que a adaptação em português do questionário pode ser utilizado na prática clínica como um instrumento de medida para as dificuldades cotidianas provocadas pelo zumbido naqueles indivíduos que o percebem. ABSTRACT OBJECTIVE: The Tinnitus Handicap Inventory is a questionnaire for assessing the impact of tinnitus by quantifying psychoemotional and functional problems it causes. The objective of the study was to validate the Brazilian Portuguese translation of this questionnaire, named Questionário de Gravidade do Zumbido. DESCRITORES METHODS:The questionnaire was applied to 135 individuals with tinnitus from two audiology clinics in Bauru, Southeastern Brazil, referred for audiologic evaluation. Its internal consistency was evaluated by Cronbach's α coefficients comparing the Brazilian version to the original instrument. RESULTS:It was found good reliability for scales (0.76<α<0.85) and for the whole questionnaire, which global consistency value (α=0.93) was identical to the original instrument.

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“…Studies show that, in extreme cases, such disturbances may lead people to commit suicide. Lewis et al 7 reports the cases of 28 patients who committed suicide due to tinnitus, pointing out the significant prevalence of elderly, male individuals with social withdrawal among the risk factors. Johnston and Walker 8 also studied suicidal patients of psychiatric clinics, featuring them as people who suffered from untreatable tinnitus, communication impairment and hopelessness as common specificities among the researched subjects.…”

Section: Introductionmentioning

confidence: 99%