Tinnitus Handicap Inventory for Evaluating Treatment Effects

Zeman, Florian; Koller, Michael; Figueiredo, Ricardo Rodrigues; Aazevedo, Andreia; Rates, Marcello; Coelho, Cláudia; Kleinjung, Tobias; Ridder, Dirk De; Langguth, Berthold; Landgrebe, Michael

doi:10.1177/0194599811403882

Cited by 186 publications

(188 citation statements)

References 24 publications

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“…The total score on the THI can be calculated by adding the scores per item. A decrease of 20 points in the THI after an intervention is considered to be an indication for a successful treatment, although a recent study suggested a decrease of 7 points to be relevant [Zeman et al, 2011] • The Tinnitus Handicap Questionnaire (THQ) measures the patients' perceived degree of handicap due to tinnitus. Patients scored their agreement with 27 different items on a scale from 0 to 100 (0 = I strongly disagree, 100 = I strongly agree).…”

Section: Methodsmentioning

confidence: 99%

Changes in Tinnitus after Cochlear Implantation and Its Relation with Psychological Functioning

et al. 2014

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This study retrospectively assessed the prevalence of tinnitus in cochlear implant patients and the changes after implantation in 212 patients implanted between 2000 and 2009. Patients were included at least 6 months after implantation and received 2 sets of questionnaires, one about the situation before implantation and one about the situation after implantation. Mostly standardized questionnaires assessed tinnitus handicap (Tinnitus Handicap Inventory, THI, and Tinnitus Handicap Questionnaire, THQ), tinnitus characteristics, hearing loss (Abbreviated Profile of Hearing Aid Benefit) and anxiety/depression (Hospital Anxiety and Depression Scale). Of the approached patients, 117 completed the full sets of questionnaires and 35 completed a short version. Preoperative tinnitus was reported by 51.3% of these patients, of which 55.6% reported a reduction or cessation of their tinnitus after implantation. However, 8.2% of the patients with tinnitus reported a postoperative deterioration of their tinnitus. In addition, among the patients without preoperative tinnitus, 19.6% reported the start of tinnitus after implantation. The self-reported change of tinnitus correlated with the pre- and postoperative scores on the THI and THQ. The THQ showed slightly more changes in scores after cochlear implantation compared to the THI. Overall hearing handicap and feelings of anxiety and depression decreased after implantation. In conclusion, tinnitus is reduced after cochlear implantation in an important part of the patients, but in a small part implantation has a negative effect on tinnitus. When tinnitus starts after implantation, the tinnitus handicap is mild.

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Section: Methodsmentioning

confidence: 99%

Changes in Tinnitus after Cochlear Implantation and Its Relation with Psychological Functioning

et al. 2014

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“…For this purpose, we calculated a paired Student's t test. Beneficial THI response was defined as a minimum change of seven points in the THI from baseline to week 3 [46]. In addition, positive treatment response was also indicated by a CGI score B3 at week 3.…”

Section: Methodsmentioning

confidence: 99%

Treatment of chronic tinnitus with repeated sessions of prefrontal transcranial direct current stimulation: outcomes from an open-label pilot study

et al. 2011

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Tinnitus is the perception of sound in the absence of an environmental sound source. Abnormal activity in central auditory pathways is considered as the neuronal correlate of tinnitus. However, there is increasing evidence from neuroimaging studies for an additional involvement of the frontal cortex in the pathophysiology of tinnitus, especially concerning its attentional and emotional aspects. Recently, in a subgroup of tinnitus patients, temporary reduction of tinnitus intensity and tinnitus-related distress has been reported after bifrontal tDCS with the anode over the right and the cathode over the left dorsolateral prefrontal cortex (DLPFC). The aim of this study was to investigate whether repeated application of bifrontal tDCS results in longer-lasting reduction of tinnitus and may represent a potential treatment approach. Thirty-two patients with chronic and treatment-resistant tinnitus received six sessions of bifrontal tDCS (1.5 mA, 30 min, two sessions per week) with the anode over the right and the cathode over the left DLPFC. Treatment outcome was assessed with several standardized tinnitus questionnaires, numeric rating scales, and a depression scale. In the entire group, beneficial effects of bifrontal tDCS on tinnitus were found for numeric rating scores of loudness, unpleasantness, and discomfort, but not in tinnitus or depression scales. Exploratory analysis revealed an effect of gender on treatment effects with female patients demonstrating a better response in several scores. Our open-label pilot study suggests some beneficial effect of bifrontal tDCS (anode right and cathode left) in the treatment of severe tinnitus, warranting further controlled studies.

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“…We based our sample size calculation on the effect size determined by Zeman and colleagues [38]. They calculated an effect size of 1.01 for a much better/very much better response by comparing the change in THI score to CGI scores for a pooled population of chronic tinnitus patients (n=210) following different treatments for tinnitus [38].…”

Section: Statisticsmentioning

confidence: 99%

Transcranial Direct Current Stimulation for the Treatment of Chronic Tinnitus: A Randomized Controlled Study

et al. 2015

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Tinnitus Handicap Inventory for Evaluating Treatment Effects

Abstract: Two different methods yielded comparable results in identifying a reduction in the THI score of 6 and 7 points, respectively, as the minimal clinically relevant change. This study provides a first orientation for sample size calculations and for planning the design of future studies.

Cited by 186 publications

References 24 publications

Changes in Tinnitus after Cochlear Implantation and Its Relation with Psychological Functioning

Changes in Tinnitus after Cochlear Implantation and Its Relation with Psychological Functioning

Treatment of chronic tinnitus with repeated sessions of prefrontal transcranial direct current stimulation: outcomes from an open-label pilot study

Transcranial Direct Current Stimulation for the Treatment of Chronic Tinnitus: A Randomized Controlled Study

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