2021
DOI: 10.3390/antiox10050681
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Tissue Antioxidant Status and Lipid Peroxidation Are Related to Dietary Intake of n-3 Polyunsaturated Acids: A Rabbit Model

Abstract: Polyunsaturated fatty acid (PUFA) metabolism and tissue distribution is modulated by the oxidation of these molecules. This research aimed to investigate the implication of dietary n-3 PUFA supplementation (precursor and long-chain PUFA) on the PUFA profile and oxidative status of the liver, testis, and brain of adult rabbit bucks. Twenty New Zealand White rabbit bucks were divided into four experimental groups (n = 5 per group) and were fed different diets for 110 days: control (CNT), standard diet containing… Show more

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Cited by 15 publications
(23 citation statements)
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“…Testicles contain reproductive tissues and cells that are involved in spermatogenesis with a clear role in long-chain polyunsaturated fatty acids (LCPUFAs) production [ 91 ]. Nevertheless, testicles are considered oxidation-sensitive organs due to higher PUFAs [ 92 ]. It is well known that PUFAs are susceptible to oxidation via free radicals [ 92 ] due to their double bonds between the carboxyl chain [ 93 ].…”
Section: Role Of Antioxidant Against Pufas’ Vulnerability To Oxidationmentioning
confidence: 99%
See 2 more Smart Citations
“…Testicles contain reproductive tissues and cells that are involved in spermatogenesis with a clear role in long-chain polyunsaturated fatty acids (LCPUFAs) production [ 91 ]. Nevertheless, testicles are considered oxidation-sensitive organs due to higher PUFAs [ 92 ]. It is well known that PUFAs are susceptible to oxidation via free radicals [ 92 ] due to their double bonds between the carboxyl chain [ 93 ].…”
Section: Role Of Antioxidant Against Pufas’ Vulnerability To Oxidationmentioning
confidence: 99%
“…Nevertheless, testicles are considered oxidation-sensitive organs due to higher PUFAs [ 92 ]. It is well known that PUFAs are susceptible to oxidation via free radicals [ 92 ] due to their double bonds between the carboxyl chain [ 93 ]. Although seminal plasma contains reactive oxygen species (ROS) scavengers, dietary inclusion of PUFAs cause an imbalance of the antioxidant.…”
Section: Role Of Antioxidant Against Pufas’ Vulnerability To Oxidationmentioning
confidence: 99%
See 1 more Smart Citation
“…Organisms have evolved molecular systems, including enzymes (metalloproteins such as superoxide dismutase and catalase [10], as well as thiol-based redox couples) [11] and non-enzymatic substances (i.e., glutathione, tocols, ascorbic acid (AA) and carotenoids) [12], to scavenge ROS or to react with them in order to maintain their physiological effects [8]. In fact, controlled generation of ROS, particularly hydrogen peroxide (H 2 O 2 ), modulates virtually all cellular processes and is essential for living systems.…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, in male rabbits fed a diet rich in PUFAs, there are increased LC-PUFA concentrations in the sperm and testes, which positively affects sperm kinetics [14]. However, these positive effects are only found when the animals have a concomitant increase in antioxidant intake (vitamin E, vitamin C and/or Selenium) to counteract MDA generation [12,24,25].…”
Section: Introductionmentioning
confidence: 99%