Tissue Characterization of the Myocardium

Pattanayak, Puskar; Bleumke, David A

doi:10.1016/j.rcl.2014.11.005

Cited by 28 publications

(18 citation statements)

References 67 publications

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“…CMR with late gadolinium enhancement, in particular, shows wide variation in quantifying focal fibrosis and cannot detect diffuse fibrosis [31, 32]. Other CMR approaches, such as T1 mapping and extracellular volume mapping, are affected by specific CMR techniques and magnetic field strength; they lack reference ranges, and there is a significant overlap of T1 mapping values of healthy and disease states [31, 32]. …”

Section: Myocardial Viability and Fibrosismentioning

confidence: 99%

Cardiac Resynchronization Therapy Optimization: A Comprehensive Approach

et al. 2019

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Since the first report on biventricular pacing in 1994, cardiac resynchronization therapy (CRT) has become standard for patients with advanced heart failure (HF) and ventricular conduction delay. CRT improves myocardial function by resynchronizing myocardial contraction, which results in reverse left ventricular remodeling and improves symptoms and clinical outcomes. Despite the accelerated development of CRT device technology and its increased application in treating HF patients, almost one-third of these patients do not respond to the therapy or gain any clinical benefit from device implantation. Over the last decade, multiple cardiac imaging modalities have provided a deeper understanding of myocardial pathophysiology, thereby improving HF treatment management. However, the optimal strategy for improving the CRT response remains debatable. This article provides an updated overview of the electropathophysiology of myocardial dysfunction in ventricular conduction delay and the diagnostic approaches involving the use of multiple modalities.

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Section: Myocardial Viability and Fibrosismentioning

confidence: 99%

Cardiac Resynchronization Therapy Optimization: A Comprehensive Approach

et al. 2019

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“…Med CT kan arr og annen fibrose påvises svaert nøyaktig, men av strålingshygieniske hensyn utføres det sjelden (19). Fibrosevurdering ved hjerte-CT har vist godt samsvar med hjerte-MR-metoder og histologi (17). Metoden vurderes ved kontraindikasjoner mot MR (17) og ved andre indikasjoner for hjerte-CT (27).…”

Section: Ct-undersøkelse Av Hjertetunclassified

“…Myokardfibrose er assosiert med økt myokardstivhet, kardiomyocyttdød, arytmier, plutselig hjertedød og ugunstig prognose (2, 3, 17, 18, 23, 28), og er sentral i remodelleringsprosessen som leder til hjertesvikt (10,17,26). Kransåresykdom, aortastenose og hypertensjon utgjør de hyppigste årsakene til myokardfibrose (13).…”

Section: Myokardfibrose Ved Ulike Sykdomstilstanderunclassified

Myokardfibrose

Espeland¹,

Lunde²,

Amundsen³

et al. 2018

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Institutt for sirkulasjon og bildediagnostikk Norges teknisk-naturvitenskapelige universitet og Klinikk for hjertemedisin St. Olavs hospital Han har bidratt med idé til artikkelen, utforming/design, datainnsamling, analyse av data, tolking av data, litteratursøk, utarbeiding/revisjon av selve manuset og godkjenning av innsendte manusversjon. Torvald Espeland er stipendiat, spesialist i indremedisin og lege i spesialisering i hjertesykdommer. Forfatter har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter.

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“…A GLS ≤−11.6% showed a sensitivity of 65% and a specificity of 75% to predict significant FMF (LGE > 10%) [43]. The majority of studies dealing with this issue have focused on DMF [15, 19, 24, 46, 47]. Of the conventional echocardiography-derived parameters, DMF seems to show a significant, though weak, correlation only with LV mass and the LV mass index [23, 24].…”

Section: Relationship Between Myocardial Fibrosis and LV Systolic Funmentioning

confidence: 99%

“…Other limitations need also mentioned. First of all, CMR-derived assessment of FMF using LGE has a wide interobserver variability, depends on the technical setting of the scanner, and does not allow detection of DMF [47]. The CMR-T1-derived T1 relaxation time and ECV are dependent on a specific CMR-T1 sequence, magnetic field strength, and homogeneity.…”

Section: Limitationsmentioning

confidence: 99%

Imaging of Myocardial Fibrosis and Its Functional Correlates in Aortic Stenosis: A Review and Clinical Potential

et al. 2018

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Patients with severe aortic stenosis (AS) show progressive fibrotic changes in the myocardium, which may impair cardiac function and patient outcomes even after successful aortic valve replacement. Detection of patients who need an early operation remains a diagnostic challenge as myocardial functional changes may be subtle. In recent years, speckle tracking echocardiography (STE) and cardiac magnetic resonance mapping have been shown to provide complementary information for the assessment of left ventricular mechanics and identification of subtle damage by focal or diffuse myocardial fibrosis, respectively. Little is known, however, about how focal and diffuse myocardial fibrosis occurring in severe AS are related to measurable functional changes by echocardiography and to which extent both parameters have prognostic and diagnostic value. The aims of this review are to discuss the occurrence of focal and diffuse myocardial fibrosis in patients with severe AS and to explore their relation with myocardial function, determined by STE, as well as the prognostic and diagnostic potential of both parameters.

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Tissue Characterization of the Myocardium

Cited by 28 publications

References 67 publications

Cardiac Resynchronization Therapy Optimization: A Comprehensive Approach

Cardiac Resynchronization Therapy Optimization: A Comprehensive Approach

Myokardfibrose

Imaging of Myocardial Fibrosis and Its Functional Correlates in Aortic Stenosis: A Review and Clinical Potential

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