Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China

Chen, Jun; Xie, Ping

doi:10.1016/j.toxicon.2005.01.003

Cited by 194 publications

(92 citation statements)

References 40 publications

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“…Extraction of MCs in the organs (≈ 0.5 g lyophilized sample for each organ) of the study animals basically followed the method of Chen and Xie (2005a).…”

Section: Methodsmentioning

confidence: 99%

In situ studies on the bioaccumulation of microcystins in the phytoplanktivorous silver carp (Hypophthalmichthys molitrix) stocked in Lake Taihu with dense toxic Microcystis blooms

et al. 2006

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“…Extraction of MCs in the organs (≈ 0.5 g lyophilized sample for each organ) of the study animals basically followed the method of Chen and Xie (2005a).…”

Section: Methodsmentioning

confidence: 99%

In situ studies on the bioaccumulation of microcystins in the phytoplanktivorous silver carp (Hypophthalmichthys molitrix) stocked in Lake Taihu with dense toxic Microcystis blooms

et al. 2006

Self Cite

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“…Elution from the cartridges with 10 ml methanol (100%) was evaporated to dryness. The residue was dissolved with 100 ll distilled water and used for the final detection and identification of MCs by LC-MS. MC concentration was measured according to the methods described by Chen and Xie (2005).…”

Section: Methodsmentioning

confidence: 99%

Factors Shaping the Pattern of Seasonal Variations of Microcystins in Lake Xingyun, a Subtropical Plateau Lake in China

Xie

et al. 2007

Bull Environ Contam Toxicol

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“…In the natural environment, MCs accumulate in a wide range of aquatic animals, including fish (Magalhães et al, 2003;Mohamed et al, 2003), shrimps (Chen and Xie, 2005b), gastropods (Chen and Xie, 2005b;Zhang et al, 2012;Zurawell et al, 1999) and bivalves (Chen and Xie, 2005a;Williams et al, 1997). MCs are found in both the viscera and also in the edible muscle/foot.…”

Section: Introductionmentioning

confidence: 99%

Bioaccumulation of microcystins (MCs) in four fish species from Lake Taihu, China: Assessment of risks to humans

Jia

Luo

Lü

et al. 2014

Science of The Total Environment

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Microcystins (MCs) are the toxic products of harmful algal blooms and they accumulate in fish. The accumulation of MCs in fish living in different trophic levels from different parts of Lake Taihu was determined. This information was then used to evaluate the risks posed by the MCs in fish to human health. The concentrations of three MCs, MC-LR, MC-YR and MC-RR, were quantified in the following four fish species: silver carp (Hypophthalmichthys molitrix), bighead carp (Aristichthys nobilis), crucian carp (Carassius auratus) and common carp (Cyprinus carpio), using high performance liquid chromatography interfaced with tandem (triple quadrupole) mass spectrometry. The mean concentrations of MCs in the muscle, the kidney, the intestinal wall and the heart were significantly different among the four fishes except in the liver. C. carpio contained the highest mean concentration of MCs in the muscle (31.7 ± 12.1 ng/g, dry mass (dm)), whereas C. auratus had the highest mean concentrations of MCs in the liver (45.4 ± 44.5 ng/g, dm), kidney (114 ± 51.1 ng/g, dm), intestinal wall (2.04 × 10 3 ± 4.43 × 10 3 ng/g, dm) and heart (59.5 ± 26.7 ng/g, dm). The mean concentration of MCs in the intestinal walls of the fish species was significantly higher than in other organs (p b 0.01). The fish from Meiliang Bay had significantly higher concentrations of MCs than those from the centre, west or south banks of the lake (p b 0.01). The body lengths and masses of the fish were negatively correlated with the concentrations of MCs in the kidney (p b 0.05) and heart (p b 0.01). The average daily intake (ADI) of MCs in the muscle of all fishes exceeded the provisional tolerable daily intake (TDI) set by World Health Organization. The estimated daily intakes of MCs in 55.6% of the muscle samples exceeded the TDI. The MCs in the tissues of the fish from Lake Taihu pose potential risks to the health of humans who consume these four fish species.

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Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China

Cited by 194 publications

References 40 publications

In situ studies on the bioaccumulation of microcystins in the phytoplanktivorous silver carp (Hypophthalmichthys molitrix) stocked in Lake Taihu with dense toxic Microcystis blooms

In situ studies on the bioaccumulation of microcystins in the phytoplanktivorous silver carp (Hypophthalmichthys molitrix) stocked in Lake Taihu with dense toxic Microcystis blooms

Factors Shaping the Pattern of Seasonal Variations of Microcystins in Lake Xingyun, a Subtropical Plateau Lake in China

Bioaccumulation of microcystins (MCs) in four fish species from Lake Taihu, China: Assessment of risks to humans

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