2010
DOI: 10.1111/j.1399-3062.2010.00505.x
|View full text |Cite
|
Sign up to set email alerts
|

Tissue donation and virus safety: more nucleic acid amplification testing is needed

Abstract: In tissue and organ transplantation, it is of great importance to avoid the transmission of blood-borne viruses to the recipient. While serologic testing for anti-human immunodeficiency virus (HIV)-1 and -2, anti-hepatitis C virus (HCV), hepatitis B surface antigen (HBsAg), anti-hepatitis B core antigen (HBc), and Treponema pallidum infection is mandatory, there is until now in most countries no explicit demand for nucleic acid amplification testing (NAT) to detect HIV, hepatitis B virus (HBV), and HCV infecti… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
29
0
1

Year Published

2011
2011
2017
2017

Publication Types

Select...
7
3

Relationship

1
9

Authors

Journals

citations
Cited by 45 publications
(30 citation statements)
references
References 52 publications
0
29
0
1
Order By: Relevance
“…Several factors have contributed to improved allograft safety: the better performance of serological assays for infectious disease testing [41], the screening and selection of the donors, the processing protocol used by the bone bank, guidelines and recommendations of scientific associations, national and international regulation and the importance of programmes of biovigilance.…”
Section: Discussionmentioning
confidence: 99%
“…Several factors have contributed to improved allograft safety: the better performance of serological assays for infectious disease testing [41], the screening and selection of the donors, the processing protocol used by the bone bank, guidelines and recommendations of scientific associations, national and international regulation and the importance of programmes of biovigilance.…”
Section: Discussionmentioning
confidence: 99%
“…The implementation of nucleic acid testing for HIV, HBV and HCV could be useful, depending on the type of tissue and their donor : recipient ratio (Pruss et al, 2010). Finally, to examine samples obtained post-mortem, there are only a few tests that are validated and CE (European Conformity)-recognized.…”
Section: Control Groupmentioning
confidence: 99%
“…As the goal of NAT is to identify infection cases falsely detected by serological assays, higher standards should be set for the sensitivity of NAT systems (15). As a result, the most advanced technique, real-time PCRbased NAT, has been developed to reduce this risk (10,16).…”
Section: Introductionmentioning
confidence: 99%