2020
DOI: 10.3389/fbioe.2020.00083
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Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia

Abstract: Exploring innovative solutions to improve the healthcare of the aging and diseased population continues to be a global challenge. Among a number of strategies toward this goal, tissue engineering and regenerative medicine (TERM) has gradually evolved into a promising approach to meet future needs of patients. TERM has recently received increasing attention in Asia, as evidenced by the markedly increased number of researchers, publications, clinical trials, and translational products. This review aims to give a… Show more

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Cited by 195 publications
(115 citation statements)
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“…A consistently increasing trend for publications in tissue engineering research over the past ten years also reflects the expansion of worldwide interest in this issue ( Figure 2 ). Cartilage, bone, skin, tooth, cardiac, and vascularization are the most popular topics discussed regarding tissue regeneration [ 11 , 12 , 13 , 14 , 15 , 16 ]. According to the Scopus database, the number of publications that relate to “tissue engineering” and bone increased more than two-fold between 2009 (1352) and 2019 (2868) ( Figure 2 ).…”
Section: Introductionmentioning
confidence: 99%
“…A consistently increasing trend for publications in tissue engineering research over the past ten years also reflects the expansion of worldwide interest in this issue ( Figure 2 ). Cartilage, bone, skin, tooth, cardiac, and vascularization are the most popular topics discussed regarding tissue regeneration [ 11 , 12 , 13 , 14 , 15 , 16 ]. According to the Scopus database, the number of publications that relate to “tissue engineering” and bone increased more than two-fold between 2009 (1352) and 2019 (2868) ( Figure 2 ).…”
Section: Introductionmentioning
confidence: 99%
“…Tissue engineering evolved from the field of biomaterials; its purpose is to combine scaffolds, cells, and biologically active molecules to obtain multifunctional materials that restore, maintain or improve damaged tissues or an entire organ. Some examples of Food and Drug Administration (FDA)-approved engineered tissues include artificial skin and cartilage, but they have limited use in human medicine due to several yet unknown aspects regarding their long term biocompatibility [ 4 , 5 , 6 , 7 , 8 , 9 ]. Bioactive scaffolds, cell therapy, smart drug delivery systems, and wound healing mats are some representative examples of the research topics approached by TE.…”
Section: Introductionmentioning
confidence: 99%
“…Bioactive scaffolds, cell therapy, smart drug delivery systems, and wound healing mats are some representative examples of the research topics approached by TE. In addition to medical applications, non-therapeutic findings include the use of tissues as biosensors to detect chemical or biological threats or the development of organs-on-a-chip for toxicity screening of experimental medication [ 4 , 8 , 10 ].…”
Section: Introductionmentioning
confidence: 99%
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“…Lastly, collagen holds the typical nanotopography piece, indifference to the same. [18][19][20] Cells from various sources of human like cardiac stem cells, bone marrow stem cells, mesenchymal stem cells, hemotoprostic stem cells, embryonic stem cells and so on have exploited for the purpose of regenerative myocardium tissues. Even though cell therapies made by different forms of cells have been favorable to improve the function of cardiac, they are not the real accepted occupier of heart tissues.…”
Section: Introductionmentioning
confidence: 99%