Tissue engineering scaffolds using superstructures

Wintermantel, E.; Mayer, J.; Blum, J.; Eckert, K.-L.; Lüscher, Patrik; Mathey, M.

doi:10.1016/0142-9612(96)85753-x

Cited by 212 publications

(90 citation statements)

References 9 publications

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“…Over the past decade, research has continued on the development of braided, laminated, and unidirectional fiberoriented PEEK fracture fixation plates, as well as extruded PEEK screws [125][126][127][128][129]. These papers describe perceived limitations in the manufacturability of the complex composites as historical barriers to the use of CFR-PEEK as fracture fixation plates.…”

Section: Trauma Implantsmentioning

confidence: 99%

PEEK biomaterials in trauma, orthopedic, and spinal implants

Kurtz

Devine²

2007

Biomaterials

2,020

1,518

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Since the 1980s, polyaryletherketones (PAEKs) have been increasingly employed as biomaterials for trauma, orthopedic, and spinal implants. We have synthesized the extensive polymer science literature as it relates to structure, mechanical properties, and chemical resistance of PAEK biomaterials. With this foundation, one can more readily appreciate why this family of polymers will be inherently strong, inert, and biocompatible. Due to its relative inertness, PEEK biomaterials are an attractive platform upon which to develop novel bioactive materials, and some steps have already been taken in that direction, with the blending of HA and TCP into sintered PEEK. However, to date, blended HA-PEEK composites have involved a trade-off in mechanical properties in exchange for their increased bioactivity. PEEK has had the greatest clinical impact in the field of spine implant design, and PEEK is now broadly accepted as a radiolucent alternative to metallic biomaterials in the spine community. For mature fields, such as total joint replacements and fracture fixation implants, radiolucency is an attractive but not necessarily critical material feature.

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Section: Trauma Implantsmentioning

confidence: 99%

PEEK biomaterials in trauma, orthopedic, and spinal implants

Kurtz

Devine²

2007

Biomaterials

2,020

1,518

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“…The surface topology of the cell scaffold materials affects the cell behavior and functions [10,87]. Plasma etching, in which materials are ablated via reactions with active species generated in the plasma to form volatile products, can create the desirable micro-features and macro-features on the biomaterials to meet the requirement of biocompatibility in vivo.…”

Section: Surface Morphologymentioning

confidence: 99%

Plasma-surface modification of biomaterials

Chu

Chen

Wang

et al. 2002

Materials Science and Engineering: R: Reports

1,423

652

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Plasma-surface modification (PSM) is an effective and economical surface treatment technique for many materials and of growing interests in biomedical engineering. This article reviews the various common plasma techniques and experimental methods as applied to biomedical materials research, such as plasma sputtering and etching, plasma implantation, plasma deposition, plasma polymerization, laser plasma deposition, plasma spraying, and so on. The unique advantage of plasma modification is that the surface properties and biocompatibility can be enhanced selectively while the bulk attributes of the materials remain unchanged. Existing materials can, thus, be used and needs for new classes of materials may be obviated thereby shortening the time to develop novel and better biomedical devices. Recent work has spurred a number of very interesting applications in the biomedical field. This review article concentrates upon the current status of these techniques, new applications, and achievements pertaining to biomedical materials research. Examples described include hard tissue replacements, blood contacting prostheses, ophthalmic devices, and other products. #

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“…The structural scaffolds are formed from structural elements such as pores, fibers or membranes, which can be ordered according to stochastic, fractal or periodic principles and can also be manufactured reproducibly using engineering ap-proaches [21][22][23]. When a 3-D tissue structure is used to develop artificial tissue substitutes, one can even engineer structural design of the biomaterial in the scaffolding architecture to optimize structural and nutritional conditions.…”

Section: Introductionmentioning

confidence: 99%

Recent development on computer aided tissue engineering — a review

Sun¹,

Lal²

2002

Computer Methods and Programs in Biomedicine

333

164

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The utilization of computer-aided technologies in tissue engineering has evolved in the development of a new field of computer-aided tissue engineering (CATE). This article reviews recent development and application of enabling computer technology, imaging technology, computer-aided design and computer-aided manufacturing (CAD and CAM), and rapid prototyping (RP) technology in tissue engineering, particularly, in computer-aided tissue anatomical modeling, three-dimensional (3-D) anatomy visualization and 3-D reconstruction, CAD-based anatomical modeling, computer-aided tissue classification, computer-aided tissue implantation and prototype modeling assisted surgical planning and reconstruction.

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Tissue engineering scaffolds using superstructures

Cited by 212 publications

References 9 publications

PEEK biomaterials in trauma, orthopedic, and spinal implants

PEEK biomaterials in trauma, orthopedic, and spinal implants

Plasma-surface modification of biomaterials

Recent development on computer aided tissue engineering — a review

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