Tissue invasion of laboratory-reared Biomphalaria glabrata by a harpacticoid copepod

Sullivan, John T.; Yeung, John T.

doi:10.1016/j.jip.2011.03.002

Cited by 4 publications

(3 citation statements)

References 4 publications

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“…Free rotifers were seen traversing the surface of the snail's shell and occasionally entering into the mantle cavity. Likewise, a similar performance of copepods invading snails was previously noticed by investigators; copepods-aided by their vigorous movements-were able to penetrate through the surface epithelium of the snail's body wall and invade the underlying tissues [32] . In another study, it was noticed that attachment of rotifers to could induce a hole in the snail's umbilicus [21] .…”

Section: Discussionsupporting

confidence: 75%

New scope on the relationship between rotifers and Biomphalaria alexandrina snails

Mossallam

Amer

Abou-El-Naga

2013

Asian Pacific Journal of Tropical Biomedicine

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Section: Discussionsupporting

confidence: 75%

New scope on the relationship between rotifers and Biomphalaria alexandrina snails

Mossallam

Amer

Abou-El-Naga

2013

Asian Pacific Journal of Tropical Biomedicine

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“…It has been extensively demonstrated that B. glabrata are confronted with metazoan parasites (nematodes or trematodes) and play the role of the intermediate vector in the human Schistosoma life cycle ( 86 – 89 ). Albeit rare, crustacean infection has been experimentally demonstrated too ( 90 ). Despite being pulmonated, Biomphalaria snails are dependent on wetland ecosystems and must also be confronted with fungal ( 91 ) or microbial infections ( 92 ).…”

Section: Discussionmentioning

confidence: 99%

New Insights Into Biomphalysin Gene Family Diversification in the Vector Snail Biomphalaria glabrata

et al. 2021

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Aerolysins initially characterized as virulence factors in bacteria are increasingly found in massive genome and transcriptome sequencing data from metazoans. Horizontal gene transfer has been demonstrated as the main way of aerolysin-related toxins acquisition in metazoans. However, only few studies have focused on their potential biological functions in such organisms. Herein, we present an extensive characterization of a multigene family encoding aerolysins - named biomphalysin - in Biomphalaria glabrata snail, the intermediate host of the trematode Schistosoma mansoni. Our results highlight that duplication and domestication of an acquired bacterial toxin gene in the snail genome result in the acquisition of a novel and diversified toxin family. Twenty-three biomphalysin genes were identified. All are expressed and exhibited a tissue-specific expression pattern. An in silico structural analysis was performed to highlight the central role played by two distinct domains i) a large lobe involved in the lytic function of these snail toxins which constrained their evolution and ii) a small lobe which is structurally variable between biomphalysin toxins and that matched to various functional domains involved in moiety recognition of targets cells. A functional approach suggests that the repertoire of biomphalysins that bind to pathogens, depends on the type of pathogen encountered. These results underline a neo-and sub-functionalization of the biomphalysin toxins, which have the potential to increase the range of effectors in the snail’s immune arsenal.

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“…According to reports found in the literature, this mollusk combines in its biology, primordial characteristics to a good environmental bioindicator, such as greater sensitivity to pollutants, not presenting a physiological adaptation to them under controlled conditions, has continuous and rapid reproduction throughout the year, allowing the performance of experiments at room temperature. In addition to these characteristics, B. glabrata also has a wide geographic distribution, low dispersion, easy capture and maintenance to laboratory conditions, short life cycle, low physical space and low-cost maintenance [11,12,13].…”

Section: Introductionmentioning

confidence: 99%

Oxidative stress in mollusks Biomphalaria glabrata exposed to gamma radiation

et al. 2018

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Ionizing radiation can cause biological changes in different organisms such as mollusks from Biomphalaria glabrata species, in which alterations could be observed in the reproductive system of the specimens, prejudicing fertility and fecundity. As the changes may occur due to the lipid peroxidation caused by the action of free radicals on the gonads, the objective of this work was to evaluate the oxidative damage caused by the exposure of B. glabrata mollusks to different doses of 60 Co gamma radiation. In addition, efforts were carried out to standardize a sensitive and low-cost technique for detecting negative effects caused by high doses of ionizing radiation. For this, each mollusk group (n = 10) was submitted to 0 (control), 10, 15, 20 and 25 Gy (gammacell 60 Co, dose rate 3.53 kGy/h). The TBARS method was applied for the quantification of lipid peroxidation of the gonads of the mollusks after 24 and 48 h. ANOVA, followed by the mean comparison (Tukey) at the 5% of significance level (p<0.05), indicated high concentrations of TBARS in the gonads after 24 h. Otherwise, after 48 h, differences for TBARS concentrations were not significant, determining that the action of free radicals from ionizing radiation on cell membranes mainly occurred within 24 h after irradiation. Therefore, the TBARS assay could be applied for detecting oxidative stress caused by short exposure of B. glabrata to ionizing radiation.

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Tissue invasion of laboratory-reared Biomphalaria glabrata by a harpacticoid copepod

Cited by 4 publications

References 4 publications

New scope on the relationship between rotifers and Biomphalaria alexandrina snails

New scope on the relationship between rotifers and Biomphalaria alexandrina snails

New Insights Into Biomphalysin Gene Family Diversification in the Vector Snail Biomphalaria glabrata

Oxidative stress in mollusks Biomphalaria glabrata exposed to gamma radiation

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