Tissue Pressure (Intracutaneous, Subcutaneous, and Intramuscular) as Related to Venous Pressure, Capillary Filtration, and Other Factors 12

Wells, Herbert; Youmans, John B.; Miller, David

doi:10.1172/jci100976

Cited by 87 publications

(21 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, a change in posture from supine to upright, increasing local intravenous pressure by about 70-80 mmHg, elevates intramuscular pressure in the anterior tibial muscle by 7-10 mmHg (Hargens et al 1983;Ballard et al 1998;Lundin and Styf 1998). Pressure transmission from veins to the surrounding tissue is even less in muscle compartments enclosed by a loose fascia (Mayerson and Burch 1939); transmission is virtually nonexistent in locations where the vessel and surrounding tissue are not enclosed by a fascia (Wells et al 1938;Mayerson and Burch 1939). In addition, it appears unlikely that the bedrest-induced increment in tibial vein distensibility was caused by decreased edema formation in the tissue surrounding the vein, since tissue impedance measurements revealed that the rate of edema formation in the lower leg during the pressure provocation was substantially greater after than before bedrest (cf.…”

Section: Venous Distensibilitymentioning

confidence: 99%

Increased distensibility in dependent veins following prolonged bedrest

2009

View full text Add to dashboard Cite

Displacement of blood to the lower portion of the body that follows a postural transition from recumbent to erect is augmented by a prolonged period of recumbency (bedrest). Information is scarce as to what extent this augmented blood-volume shift to dependent veins is attributable to increased distensibility of the veins. Accordingly, we studied the effect of 5 weeks of horizontal bedrest on the pressure-distension relationship in limb veins. Elevation of venous distending pressure was induced by exposure of the body except the tested limb to supra-atmospheric pressure with the subject seated in a pressure chamber with one arm, or supine with a lower leg, protruding through a hole in the chamber door. Diameter changes in response to an increase of intravenous pressure (distensibility) from 60 to about 140 mmHg were measured in the brachial and posterior tibial veins using ultrasonographic techniques. Prior to bedrest, the distensibility was substantially less in the tibial than in the brachial vein. Bedrest increased (P < 0.01) pressure distension in the tibial vein by 86% from 7 +/- 3% before to 13 +/- 3% after bedrest. In the brachial vein, bedrest increased (P < 0.05) pressure distension by 36% from 14 +/- 5% before to 19 +/- 5% after bedrest. Thus, removal of the gravity-dependent pressure components that act along the blood vessels in erect posture increases the distensibility of dependent veins.

show abstract

Section: Venous Distensibilitymentioning

confidence: 99%

Increased distensibility in dependent veins following prolonged bedrest

2009

View full text Add to dashboard Cite

show abstract

“…Notably, early investigators reported subcutaneous tissue pressures between zero and eight cmH 2 O in the forearm and leg for normal individuals, and exceeding 20 cmH 2 O in edematous patients. [13] The framework in which these results are viewed may additionally provide insights into the management of the circulation. CVP is often used in assessment of the volume state.…”

Section: Resultsmentioning

confidence: 99%

Influence of tissue pressure on central venous pressure/peripheral venous pressure correlation: An experimental report

Harvey

Cave

2011

World J Emerg Med

View full text Add to dashboard Cite

“…Both hydrostatic vascular pressure and the interstitial pressure COP tend to move water from capillaries, while vascular COP and interstitial hydrostatic oppose this movement. In peri pheral capillaries, such as those of the skin and subcutaneous tissues, inter stitial COP and hydrostatic pressures have been reported varying from + 5 to -15 mmHg depending on the method employed to determine this value [5,15,20,46], If one assumes a slightly positive value, as found by W id erhielm [53], then the capillary leak of fluid is dependent upon intravascular hydrostatic pressure -COP differences.…”

Section: Discussionmentioning

confidence: 99%

Physiologic Changes Associated with Increasing Pulmonary Wedge Pressures in the Dog

Glauser¹,

Hoshiko²,

Watanabe³

et al. 1974

Respiration

View full text Add to dashboard Cite

The effects of systematically increasing pulmonary wedge pressure (PWP) between baseline normal values and 30 mmHg on physiologic parameters was studied in ten mongrel dogs.After obtaining baseline normal values, the PWP was raised in stepwise increments of 5–7.5 mm Hg by inflating an intra-aortic balloon and infusing iso-oncotic fluids.The following decreased significantly at most levels of PWP measured: PaO₂, mmHg, supine (r=-0.708, p < 0.001); semi-upright (r=-0.681, p < 0.01); DLCO, ml/min/mmHg/kg (r=-0.543, p < 0.01). Circulation time (r=0.612, p < 0.01) and central blood volume (r = 0.471, p < 0.01) increased significantly at most levels of PWP observed. Upright chest X-ray changed from baseline at PWP of 19 mmHg

show abstract

Tissue Pressure (Intracutaneous, Subcutaneous, and Intramuscular) as Related to Venous Pressure, Capillary Filtration, and Other Factors 12

Cited by 87 publications

References 9 publications

Increased distensibility in dependent veins following prolonged bedrest

Increased distensibility in dependent veins following prolonged bedrest

Influence of tissue pressure on central venous pressure/peripheral venous pressure correlation: An experimental report

Physiologic Changes Associated with Increasing Pulmonary Wedge Pressures in the Dog

Contact Info

Product

Resources

About