Tissue reactivity and suture handling characteristics of “jimat” against silk and chromic gut in cat thigh muscle: A comparative study

Abstract

Aim:This study was conducted to evaluate and compare the tissue reactivity and suture handling characteristics of chromic gut, silk, and ‘jimat’ suture materials in cat thigh muscle.Materials and Methods:This experimental study was conducted from November, 2013 to April, 2014 in Kombolcha Animal Diseases Survey, Research and Diagnostic Laboratory, Kombolcha, Ethiopia. A total of 36 local breed male cats were randomly assigned into chromic gut, silk, and “jimat” groups of 12 cats each as A, B, and C, respectively. The hind leg muscle biceps femoris was incised and sutured with suture materials according to their groups. The muscle samples with its suture were collected at six different days interval i.e. 1, 3, 7, 14, 21, and 28 and processed histopathologically to assess the degree of leukocytic infiltration and fibrous and granulation tissue formation (GTF). In addition, all suture materials were evaluated intraoperatively about their handling characteristics, by rating the precision of knot tying, square knot positioning, and resistance to knot slippage. The statistical analysis was done with two-way ANOVA, Kruskal–Wallis, and Chi-square tests.Results:The histopathology showed that “jimat” thread (2.4±1.2) had produced least leukocytic infiltration than chromic gut (4.5±1.9) and silk (4.3±1.5) sutures during the study period. Higher GTF was seen at day 3 (6 [100%]), 7 (6 [100%]) and day 14 (4 [66.7%]) in all sutures, whereas “jimat” showed significantly (p<0.05) higher fibrous tissue formation (10 [83.3%]) than others. Moreover, “jimat” suture had equal suture handling characteristics (p>0.05) with both chromic gut and silk.Conclusion:The result indicated that a single strand “jimat” thread appears to be the most satisfactory suture material as regards to both tissue reaction and suture handling characteristics for skeletal muscle approximation in cats and provided that studies on its carcinogenic effects should be done.

Natural Cellulose Fibers for Surgical Suture Applications

“…Monofilament sutures, especially synthetic stitches, produce less tissue reaction than multifilament sutures. The use of multifilament sutures with several knots often elicits a more significant inflammatory response, causing more potential problems in recovery [ 37 ]. For example, Kandimalla et al [ 5 ] developed a suture biomaterial based on the ramie plant.…”

Perbandingan Tingkat Kesembuhan Luka pada Kulit Kelinci yang Dijahit Benang Bedah Absorbable (Catgut) dan Nonabsorbable (Silk) (COMPARISON OF WOUND HEALING LEVELS ON RABBIT SKIN SUTURED WITH ABSORBABLE (CATGUT) AND NONABSORBABLE (SILK) SURGICAL THREAD)

“…Pada penelitian tersebut didapatkan bahwa penjahitan yang dilakukan secara transdermal maupun subkutikuler yang menggunakan benang sutera (nonabsorbable) mempunyai perbedaan yang bermakna bila dibandingkan dengan menggunakan benang polydioxanone/PDS (absorbable). Bekele et al (2015) menyatakan bahwa masalah utama dalam pemilihan jenis benang yaitu serat benang yan g multifilamen ikut membawa kemungkinan besar terjadi infeksi, sehubungan dengan struktur benang yang dipilin. Celah yang terbentuk menyulitkan antibiotik untuk membunuh bakteri.…”

“…Darah yang mengering (keropeng)adalah manifestasi dari luka yang selalu ditemukan dalam awal proses penyembuhan luka (Bekele et al, 2015). Pada kelinci dengan perlakuan dengan benang nonabsorbable pada hari ketujuh dilakukan pengambilan benang setelah hari ke-8 pasca peng ambilan benang terjadi peningkatan jumlah keropeng.…”

“…Berdasarkan penjelasan Kumar dan Reddy (2014) pada penelitian yang dilakukan bahwa secara alami dalam proses penyembuhan luka terjadi eksudasi cairan edema. Benang yang terbuat dari bahan alami seperti benang silk menjadi masalah ketika diterapkan pada keadaan tersebut (Bekele et al, 2015). Karakter benang nonabsorbable (silk) yang dipilin menyebabkan adanya celah yang memudahkan cairan edema mengisinya dan membuat benang menjadi lunak dan menurun ketegangan benangnya sehingga simpul benang lepas karena putus (Mulon et al, 2010).…”