Tissue response to implanted ceramic‐coated titanium alloys in rats

Satomi, Keiichi; Akagawa, Yasumasa; H, Nikai; Tsuru, Hiromichi

doi:10.1111/j.1365-2842.1988.tb00166.x

Cited by 12 publications

(10 citation statements)

References 10 publications

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“…The effect of these parameters on the foreign body reaction has been described for several types of neural electrodes implanted in different locations (Szarowski et al, 2003 ; Polikov et al, 2005 ; Seymour and Kipke, 2007 ; Ortiz-Catalan et al, 2012 ). The apparent delayed healing response to the TiN implants observed here is consistent with a previous study by Satomi et al who compared the tissue reaction to various Ti based materials using a rat subcutaneous implantation model (Satomi et al, 1988 ). They have shown that the subacute tissue response to TiN was less favorable than for pure Ti implants, as evidenced by the presence of granulation tissue around TiN implants after 3 and 7 days.…”

Section: Discussionsupporting

confidence: 92%

Boron-Doped Nanocrystalline Diamond Electrodes for Neural Interfaces: In vivo Biocompatibility Evaluation

et al. 2016

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Boron-doped nanocrystalline diamond (BDD) electrodes have recently attracted attention as materials for neural electrodes due to their superior physical and electrochemical properties, however their biocompatibility remains largely unexplored. In this work, we aim to investigate the in vivo biocompatibility of BDD electrodes in relation to conventional titanium nitride (TiN) electrodes using a rat subcutaneous implantation model. High quality BDD films were synthesized on electrodes intended for use as an implantable neurostimulation device. After implantation for 2 and 4 weeks, tissue sections adjacent to the electrodes were obtained for histological analysis. Both types of implants were contained in a thin fibrous encapsulation layer, the thickness of which decreased with time. Although the level of neovascularization around the implants was similar, BDD electrodes elicited significantly thinner fibrous capsules and a milder inflammatory reaction at both time points. These results suggest that BDD films may constitute an appropriate material to support stable performance of implantable neural electrodes over time.

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Section: Discussionsupporting

confidence: 92%

Boron-Doped Nanocrystalline Diamond Electrodes for Neural Interfaces: In vivo Biocompatibility Evaluation

et al. 2016

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“…Table 2 demonstrates the duration of implantation, the animal model used, and BIC for Ti and TiN-coated materials from several in vivo studies. In yet another in vivo study in rats, the thickness of fibrous connective tissue around Ti-6Al-4V implants was found to be the same whether it was coated with TiO 2 or TiN [10]. Based on the above studies, it can be concluded that the TiN coating demonstrates a good biological response and does not negatively affect osseointegration and healing around Ti implants.…”

Section: Coatings In Implant Dentistrymentioning

confidence: 69%

Titanium Nitride and Nitrogen Ion Implanted Coated Dental Materials

et al. 2012

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Titanium nitride and/or nitrogen ion implanted coated dental materials have been investigated since the mid-1980s and considered in various applications in dentistry such as implants, abutments, orthodontic wires, endodontic files, periodontal/oral hygiene instruments, and casting alloys for fixed restorations. Multiple methodologies have been employed to create the coatings, but detailed structural analysis of the coatings is generally lacking in the dental literature. Depending on application, the purpose of the coating is to provide increased surface hardness, abrasion/wear resistance, esthetics, and corrosion resistance, lower friction, as well as greater beneficial interaction with adjacent biological and material substrates. While many studies have reported on the achievement of these properties, a consensus is not always clear. Additionally, few studies have been conducted to assess the efficacy of the coatings in a clinical setting. Overall, titanium nitride and/or nitrogen ion implanted coated dental materials potentially offer advantages over uncoated counterparts, but more investigation is needed to document the structure of the coatings and their clinical effectiveness. OPEN ACCESSCoatings 2012, 2 161

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“…Все материалы были инкапсулированы тонкой волокнистой соединительной тканью, толщина которой была значительно больше вокруг ГА, чем вокруг титана с нитридом титана на поверхности. Сделано заключение, что все указанные материалы обладают хорошей совместимостью с тканями организма и могут использоваться в клинике для зубных имплантатов [37]. Титан имеет 2 аллотропические модификации: альфа-титан устойчив к температурам до 882 °С, при более высоких температурах -переходит в бета-титан.…”

Section: особенности материалов для изготовления дентальных имплантатовunclassified

Current trends of the choice and processing of materials for dental implantation

Maiborodin

Shevela

Toder

et al. 2018

Stomat.

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For assessment of the modern situation about the choice of materials for manufacture of dental implants and the processing of their surface the scientific literature for the last 2 years was study. On the basis of a large number of contradictory results of the researches devoted to each of dental implantation problems it is possible to draw a conclusion that any of primal problems of implantology is finally not solved. There is no unique opinion at the choice of optimum material for manufacture of dental implants, at the way of processing and modification of their surface. The problem of improvement of quality of dental implantation and fight against complications of this procedure cannot be solved simple drawing other substances on the implanted material surface, this task more easily and more successfully is solved via changes of product structure and various modification of implant surface. Up to the present the researches of an opportunity to influence on characteristics of the implanted materials, changing their structure and character of a surface, continue. And the publications reporting about the considerable positive effect of artificially created roughnesses on product surfaces, and the articles claiming that there are no big differences between the rough and polished implants are confirmed by objective measurements with statistical processing of the obtained data. It should be noted that among articles there are very many works of the doubtful plan or with insufficiently valid conclusions. This review leads to the conclusion that further clinical and experimental studies and about the choice of materials for manufacture of implants and at the ways of processing of their surface are necessary.

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Tissue response to implanted ceramic‐coated titanium alloys in rats

Cited by 12 publications

References 10 publications

Boron-Doped Nanocrystalline Diamond Electrodes for Neural Interfaces: In vivo Biocompatibility Evaluation

Boron-Doped Nanocrystalline Diamond Electrodes for Neural Interfaces: In vivo Biocompatibility Evaluation

Titanium Nitride and Nitrogen Ion Implanted Coated Dental Materials

Current trends of the choice and processing of materials for dental implantation

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