Titanium Allergy in Dentistry

Tanwar, Nishi; Prakash, Chander; Chaudhary, Kuldeep; Tewari, Shikha; Bhagavatheeswaran, Subramony

doi:10.4103/ccd.ccd_773_20

Cited by 7 publications

(6 citation statements)

References 17 publications

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“…Tests for allergy to titanium or other metals Tanwar et al 75 Case report A 56-year-old male showing allergic symptoms after 1 week of dental (Ti) implant placement with no perioral or facial signs, but eczema was shown on the distant body parts, and complete remission was attained after removing the dental implant.…”

Section: Study Summarymentioning

confidence: 99%

The contribution of metal allergy to the failure of metal alloy implants, with special reference to titanium: Current knowledge and controversies

Huang,

Chiang,

Gawkrodger

2023

Contact Dermatitis

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After almost three‐quarters of a century during which contact dermatologists have often struggled to comprehend the relationship between metal allergy and failure of metal‐alloy containing implant, it is possible to say that a relationship does exist, particularly for cobalt and chromium, but also for nickel. There is still debate as to whether allergy develops as a consequent of failure but thenceforth contributes to it, or whether sensitisation starts first and induces failure secondarily—opinion probably favours the first. Metal‐on‐polypropylene articulations were associated with few metal allergic problems but now are less favoured by orthopaedists due to plastic wear products causing osteolysis and pseudotumour formation through local inflammation. New metal alloys are regularly being introduced such that interested dermatologists need to stay on top of the situation. The jury is still out as to whether the recent favouring of titanium‐containing alloys will confirm them to be more inert allergenically. Case reports do show some clinical reactions to titanium‐containing implants and patch test series have inferred sometimes quite a high background rate of allergy, but interpretation must be tempered by the awareness that titanium salts on patch testing have a tendency to cause irritant reactions. Blood monitoring of metal ion values is now recommended in certain situations after joint replacement and increasing levels may be an indication that allergy with joint failure can develop, in which case patch testing is indicated, and suggested series are available. Predictive patch testing, whilst generally not recommended in the past, has been introduced into some protocols often by non‐dermatologists, such that it is now needed for temporo‐mandibular joint and Nuss bar insertion, and it can be anticipated that this may become more commonplace in the future. One of the major current deficits for patch testers is standardised guidance on which preparation or preparations to use for suspected titanium allergy. One suggestion is 0.5% titanium sulphate in petrolatum, though experience in at least one centre suggests the use of a battery of titanium salts might be desirable.

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Section: Study Summarymentioning

confidence: 99%

The contribution of metal allergy to the failure of metal alloy implants, with special reference to titanium: Current knowledge and controversies

Huang,

Chiang,

Gawkrodger

2023

Contact Dermatitis

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“…A hipersensibilidade ao titânio é causada por macrófagos e linfócitos T, indicando hipersensibilidade do tipo IV (Tanwar et al, 2021). Tanwar et al (2021), em seu trabalho, relataram o caso de um paciente que fez a colocação de um implante de titânio e após isso ele teve reações de eczema pelo corpo, já na região perioral não apresentou reações. Radiograficamente não foi constatada nenhuma alteração ao redor do implante.…”

Section: )unclassified

“…As manifestações mais comuns a reação alérgica ao titânio são as urticárias, vermelhidão da mucosa, prurido, cicatrização retardada, edema e eczema pelo corpo (Syed et al, 2015, Hosoki et al, 2016, Graaf de et al, 2018, Tanwar et al, 2021. Pacientes que relatarem reações de hipersensibilidade a metais e joias deverão ser submetidos a teste de sensibilidade ao titânio caso necessitem fazer tratamentos contendo titânio (Hosoki et al, 2016, Tanwar et al, 2021.…”

Section: )unclassified

Reações alérgicas e suas manifestações na odontologia: revisão integrativa

Lelis

Silva²,

Borges³

et al. 2022

RSD

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Introdução: Alergia é um quadro de hipersensibilidade onde o organismo responde de maneira excessiva em contato com um antígeno. Na prática odontológica as mais comuns são as do tipo I e IV. As reações do tipo I na cavidade oral se manifestam como angioedema, sensação de ardor ou parestesia oral, enquanto nas reações de hipersensibilidade tipo IV, os sintomas são as reações liquenóides, eritema e estomatite. O presente estudo se propõe a realizar uma revisão integrativa sobre as muitas causas de reações alérgicas no âmbito odontológico e suas interrelações com outros alérgenos. Metodologia: Foram realizadas buscas nas bases de dados PubMed e LILACS utilizando os termos “allergy”, “dentistry” “materials”, “allergic reaction” e “dentist” que foram combinados usando os operadores booleanos “AND”. Foram incluídos artigos no intervalo de tempo de 2002 a 2022 na língua inglesa, portuguesa e espanhola e a busca resultou em 21 artigos. Resultados e Discussão: A odontologia vem sofrendo grandes inovações e, com isso, uma gama de materiais são desenvolvidos e disponibilizados no mercado. Mesmo criados com princípios de biocompatibilidade, há casos onde se pressupõe falhas nesse princípio, ocasionando as reações alérgicas. Essas reações são causadas por diversos materiais, sendo os mais comuns às luvas de látex, anestésicos, materiais de moldagem e metais. Conclusão: Sempre que houver suspeita de alergia a algum material, mesmo que remota, o profissional deverá alterar o protocolo de atendimento lançando mão de materiais alternativos para evitar emergências médicas no consultório odontológico.

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“…However, titanium as an implant can result in host immune reactions, magnetic resonance artifacts, metal element release, and other problems. For patients with thin gingiva, particularly the anterior teeth, it is easy to reveal the metal color of the titanium implant, and gingival recession that may exist after implant placement can also lead to metal exposure, making it difficult to adequately satisfy the individual patient's requirements for the aesthetic performance [4,5].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Sterilization Treatment on the Surface Characteristics and Biological Activity of Zirconia Implant

Niu,

Han,

Yizhe

et al. 2024

Preprint

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Zirconia implants have emerged as a promising novel material in the field of dentistry due to their ability to overcome certain limitations associated with titanium implants. However, the appropriate sterilization protocols for zirconia implants have not yet been thoroughly investigated. To address this gap, this study conducted an assessment of the surface characteristics of fully sintered 3Y-TZP zirconia slices after being subjected to various sterilization methods, including ethylene oxide (EO), hydrogen peroxide plasma (HPP), electron beam (EB), and a combination of hydrogen peroxide plasma with either ethylene oxide (HPP+EO) or electron beam treatment (HPP+EB). Although the HPP treatment group did not demonstrate the highest level of hydrophilicity and contamination removal, it did exhibit notable hydrophilicity, effectively prevented hydrocarbon contamination, and maintained a substantial concentration of Zr. The surface of zirconia treated with HPP displayed significant enhancements in cell proliferation, cytoskeleton development, osteogenic differentiation, and adhesion capabilities for hBMSCs and HGFs, surpassing the performance of other groups. Based on these findings, the sterilization of zirconia implants using hydrogen peroxide plasma therapy appears to be a feasible technique.

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Titanium Allergy in Dentistry

Cited by 7 publications

References 17 publications

The contribution of metal allergy to the failure of metal alloy implants, with special reference to titanium: Current knowledge and controversies

The contribution of metal allergy to the failure of metal alloy implants, with special reference to titanium: Current knowledge and controversies

Reações alérgicas e suas manifestações na odontologia: revisão integrativa

The Effect of Sterilization Treatment on the Surface Characteristics and Biological Activity of Zirconia Implant

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