This paper presents a perspective of the needs and opportunities associated with the multidisciplinary problem of nondestructive evaluation (NDE) of additive manufacturing (AM). Recognizing the multidisciplinary nature of the problem, as well as the need to bridge knowledge between the different communities, the paper is structured to provide brief backgrounds and details relevant to both communities, as well as present an assessment of the state of the art. This paper, in some respects, is meant to be a primer of the different landscapes, as well as a catalyst for making future connections. At the end, it will be clear that there is much more work to be done, but that the work that is ongoing is exciting, and the potential to exploit NDE techniques for metals-based AM is very high.