Titanium dioxide coated surfaces for capillary electrophoresis and capillary electrochromatography

Abstract

The potential of titanium dioxide coatings to control the electroosmotic flow and to affect the migration behavior of analytes in capillary electrophoresis and open-tubular capillary electrochromatography was evaluated. The inner wall of a fused-silica capillary was applied with a solution of a titanium peroxo complex, followed by heating at an elevated temperature. The resultant product was ascertained to be titanium dioxide in a crystalline form of anatase by the results of Fourier transform-infrared spectrometry (FT-IR), X-ray photoelectron spectroscopy, and Raman spectroscopy. The capillary thus made had anodic or cathodic electroosmotic flow, depending on the pH and composition of the background electrolyte used. The titanium dioxide surface of the capillary was readily modified by a silanizing reagent. The performance of the titanium dioxide surfaces with or without chemical modifications was examined with inorganic anions, neutral compounds and peptides.

Application of liquid phase deposited titania nanoparticles on silica spheres to phosphopeptide enrichment and high performance liquid chromatography packings

“…For example, titania-silica composite prepared by co-precipitation has been shown to be more pH stable than silica [5]; titania-zirconia composites synthesized by the sol-gel method showed higher phosphopeptide enrichment efficiency than using single metal oxides [6]. Titania-coated separation materials have been widely used in various separation applications, particularly in high performance liquid chromatography (HPLC) [7][8][9][10], capillary electrophoresis (CE) [11][12][13][14], and solid-phase microextraction (SPME) [15][16][17][18]. Based on the Lewis acid-base interaction between titania and phosphate groups, the use of titania-coated materials has been applied in proteomics and phosphoproteomics [19][20][21][22].…”

Microchip CE analysis of amino acids on a titanium dioxide nanoparticles‐coated PDMS microfluidic device with in‐channel indirect amperometric detection

“…Titanium dioxide (TiO 2 ) has been the focus of numerous investigations in recent years, and it was first introduced in CE by Tsai et al [34] to prepare a TiO 2 -coated column using the sol-gel method for the separation of proteins in 1994. Fujimoto [35] employed TiO 2 and an ODS-modified column for the CE and CEC separation of carbohydrates and proteins. Xu et al [36] introduced a mesoporous TiO 2 film on the capillary by means of the sol-gel technique for the CE separation of alkaloids in a nonaqueous system.…”

Titanium Carbide Obtained by Magnetron Sputtering of Graphite on Heated Titanium Substrate

“…Which can be explained that at this temperature only small amount of carbon create the Ti-C bondings and the rest carbon creates a thin film at the surface of titanium substrate. At 800 °C and 900 °C there is also additional TiO2 (anatase) peak at 147 cm -1 [10]. Anatase phase occurs due to the laser induced oxidation process of titanium, which did not create bondings with carbon atoms.…”