This chapter provides an overview of important topics in human resource management (HRM) that are affected by digitalization and automation. It is outlined how work in HRM is changing in areas such as mental health at work, work design, leadership and personnel development. The last section shifts focus and introduces a new way of working in HRM, known as HR analytics or people analytics. The fact that the various topics are not independent of each other and indeed intersect with each other is illuminated in the individual sections.