For a long period of time it is believed that the ill effects of kidney disease often effect the cognitive functions. The association between chronic kidney disease (CKD) and Alzheimer's disease (AD) have been identified in many clinical studies. It is said that the improvement of the kidney function will improve the cognitive function of the individual. A 52 year old man was brought to medicine OPD with a complain of swelling of lower extremities and his family members complain about his loss of memory on some occasions. He was hospitalized and treatment was started using oral and intravenous medications.