To Be a CLABSI or Not to Be a CLABSI—That is the Question: The Epidemiology of BSI in a Large ECMO Population

Abstract

wanted to learn more about their role in stewardship, and identified venues to receive this education. Nurses with master's degrees were less likely to believe that nurses might play a role in ASPs, perhaps due to greater familiarity with the current state of ASP, and perhaps, therefore, they were less likely to think "outside the box" regarding a nursing role. Nonetheless, most nurses felt that they played a role in antimicrobial stewardship. The strengths of this study include the large number of nursing respondents across different hospitals and patient care units. The study also has several limitations. The survey had a relatively low response rate, and because responses to the survey were voluntary, respondents may not be representative of all nurses at our hospital system. Similarly, responses obtained from nurses in our institution may not be generalizable among all nurses. This study illustrates a need to educate nurses on general principles of antimicrobial stewardship, and our findings point to multiple areas for nursing-targeted interventions that merit additional research. Nurses could ensure or facilitate acquisition of proper allergy histories, blood culture techniques, prioritization of antimicrobial administration, and antimicrobial de-escalation. Given the number of bedside nurses in practice, such interventions have the potential to substantially lower inappropriate antimicrobial utilization.

Characteristics of venous‐venous extracorporeal membrane oxygenation related bloodstream infections

“…Our organism profile is similar to that reported in ECMO patients 1,2,4,6 . Amongst VV‐ECMO, common isolates include gram negative rods, candida species, and Staphylococcus/Streptococcus species 2,7,8 .…”

“…Our organism profile is similar to that reported in ECMO patients. 1,2,4,6 Amongst VV-ECMO, common isolates include gram negative rods, candida species, and Staphylococcus/Streptococcus species. 2,7,8 Compared to central venous catheter associated infections, the ECMO population microbiological spectrum shifts toward gram-negatives and fungi rather than Staphylococcus species.…”

Hospital expenses of nosocomial infection associated with extracorporeal membrane oxygenation in China: a retrospective cohort study

“…The results of this study showed that the total hospital expenses for patients among ECMO infection group and ECMO non infection group were This may be linked with the following reasons. Firstly, nosocomial infection in patients supported by ECMO is highly likely to result in the death, which can cause significant underestimation of the hospital expenses due to nosocomial infection (28). Secondly, some studies have found that prophylactic antibiotics during ECMO could reduce nosocomial infection and showed lower mortality (29,30).…”

Respiratory extracorporeal membrane oxygenation and central-line–associated bloodstream infection: Experience at a tertiary-care center during the coronavirus disease 2019 (COVID-19) pandemic

“…The overall incidence density of ECMO-CLABSI was 10.54 per 1,000 ECMO days, which is in line with other observational studies. 3,4 Respiratory ECMO use has increased since the COVID-19 pandemic began, and increasing incidence density of ECMO-CLABSI has also been observed.…”

“…2 Implicit in our perception of the problem is the assumption that it is getting inexorably worse. 3 Hospitals are seen as overcrowded, unsanitary facilities full of vulnerable patients and contaminated equipment where intense antimicrobial exposure drives the evolution of resistance. 4 Periodic updates catalog the various organisms that threaten our pharmaceutical armamentarium for any given year.…”