2021
DOI: 10.1155/2021/5520325
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To Determine Pivotal Genes Driven by Methylated DNA in Obstructive Sleep Apnea Hypopnea Syndrome

Abstract: Obstructive sleep apnea syndrome (OSAHS) is a widespread respiratory dysfunction that has attracted more and more attention in recent years. Recently, a large number of studies have shown that abnormal DNA methylation epigenetically silences genes necessary for the pathogenesis of human diseases. However, the exact mechanism of abnormal DNA methylation in OSAHS is still elusive. In this study, we downloaded the OSAHS data from the GEO database. Our data for the first time revealed 520 hypermethylated genes and… Show more

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“…Currently, the commonly used scales for cognitive function testing of OSAHS patients include Montreal Cognitive Assessment Scale (MoCA), Simple Mental State Examination Scale (MMSE), Wechsler Adult Intelligence Scale (WAIS), Extended Dementia Scale (ESD), Lowenstein Cognitive Scale Language Fluency Test (VFT), daily living activity scale, and complete neuropsychological test [ 6 ]. Because the assessment scale is relatively simple and time-consuming, it is widely used in the detection of cognitive function.…”
Section: Literature Reviewmentioning
confidence: 99%
See 1 more Smart Citation
“…Currently, the commonly used scales for cognitive function testing of OSAHS patients include Montreal Cognitive Assessment Scale (MoCA), Simple Mental State Examination Scale (MMSE), Wechsler Adult Intelligence Scale (WAIS), Extended Dementia Scale (ESD), Lowenstein Cognitive Scale Language Fluency Test (VFT), daily living activity scale, and complete neuropsychological test [ 6 ]. Because the assessment scale is relatively simple and time-consuming, it is widely used in the detection of cognitive function.…”
Section: Literature Reviewmentioning
confidence: 99%
“…The objective of this research is to study the correlation between cognitive function and AHI LSaO2 ODI in patients with OSAHS. [6]. Because the assessment scale is relatively simple and time-consuming, it is widely used in the detection of cognitive function.…”
Section: Introductionmentioning
confidence: 99%