To err is human; acute appendicitis a mistaken clinical identity for metastatic follicular thyroid carcinoma, a case report

Jusabani, Ahmed; Ismail, Neelam; Fidaali, Zainab; Mjejwa, Ramadhani; Maftah, Tausi; Ismail, Allyzain

doi:10.1016/j.ijscr.2022.107792

Cited by 1 publication

(2 citation statements)

References 17 publications

(17 reference statements)

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“…Our case is twenty-eight years old female who underwent subtotal thyroidectomy, para-umbilical hernia repair and emergency open appendectomy within 7 days; this is not similar to any international studies [1-9], our case was euthyroid status unlike other studies [5,6], our case hasn't thyroid carcinoma unlike international findings [7]. The development of acute appendicitis could be explained by the flaring phase of thyroid hormones post thyroidectomy which may exaggerated the inflammatory response leading to this presentation, this is consistent with many international studies [1][2][3][4].…”

Section: Discussioncontrasting

confidence: 47%

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Post Subtotal Thyroidectomy Acute Appendicitis, Elhassaheisa Teaching Hospital, Elhassaheisa, Sudan: 2022

Omer Taha Ahmed Elmukashfi,

Taha Ahmed Elmukashfi Elshiekh,

Mohammed Algily Dafalla Mohammed

et al. 2023

World J. Bio. Pharm. Health Sci.

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Background: Thyroid hormones have a significant role in modulating immune system. Methods: A female of twenty-eight years old, presented with anterior neck swelling of five months duration, small in size, increases gradually over time. On examinations: looked well; afebrile. There was diffuse anterior neck swelling move with swallowing, no dilated veins or ulcers, free supra sternal notch. Swelling was soft smooth surface, diffuse, not attached to muscles, and no palpable lymph nodes. Diagnosed as simple diffused goiter and underwent subtotal thyroidectomy for cosmetic. On second day post operatively, she developed acute, central abdominal colicky pain, with no relieving or aggravating factors. On examination: looked unwell, afebrile, normal abdominal contour, move with respiration, free flanks, visible para umbilical swelling, tender and irreducible. Diagnosed as incarcerated para-umbilical hernia and repair was performed. On sixth day from first operation, she developed acute severe continuous right iliac fossa pain, not radiated with no relieving or aggravating factors. On examination: looked unwell, normal abdominal contour; move with respiration, free flanks, tenderness at right iliac fossa with positive rebound tenderness. Diagnosed as acute appendicitis and underwent appendectomy. Discharged in a good condition and came to refer clinic well and free of complains. Conclusion and recommendation: Incarceration of para-umbilical hernia could be due to lifting heavy weight in ward. Development of acute appendicitis may be due to flaring phase of thyroid hormones post thyroidectomy, exaggerating inflammatory response. Evaluation and monitoring of thyroid hormones post operatively, and provision of comforts facilities for such patients, was recommended.

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Section: Discussioncontrasting

confidence: 47%

“…The surgical emergencies have rare relations with thyroid diseases which could be life threatening conditions if occur [5]. Thyrotoxicosis and thyroid storm (TS) can resemble an acute surgical abdomen [6], also metastatic right iliac bone of follicular thyroid carcinoma can mimic acute appendicitis [7].…”

Section: Introductionmentioning

confidence: 99%