To evaluate the relation between central venous pressure and inferior vena cava collapsibility in cases of pediatric shock

Abstract

Background: Invasive hemodynamic monitoring of central venous pressure (CVP) is a useful guide in directing early resuscitative efforts and assists in reducing the morbidity and mortality of the patients with septic shock. Dynamic parameters like ultrasonographic evaluation of the inferior vena cava (IVC) diameters are becoming increasingly popular method to assess the intravascular volume status. Objectives: The objective of this study was to evaluate the relation between CVP and IVC collapsibility in cases of fluid refractory shock. Methods and Materials: This was a prospective observational study. Pediatric patients between 1 and 14 years with fluid refractory shock were evaluated. Their CVP was recorded and IVC diameter was measured by ultrasonography during inspiration and expiration. This was calculated as IVC collapsibility index (IVC-CI). Data analysis was done with descriptive statistics, coefficient of correlation, and analysis of variance, as appropriate using SPSS for Windows software (SPSS Inc. Version 20). Results: A total of 107 patients with shock were included in the study with the mean age of 7.6 years. Septic shock (93%) was the most common cause of shock and the maximum patients (63%) were in cold shock. Most of these patients had acidosis (mean pH 7.22±0.2), high lactate levels (mean 6.3±3.50 mmol/l), and decreased bicarbonate levels (mean 16.98±5.95 mmol/l). When CVP range was ?8 mmHg, the mean IVCCI value was >40% and when the CVP range was ?12 mmHg, the mean IVCCI value was around 20%. Inverse relation between CVP and IVCCI was observed (r=?0.690, p<0.01). Conclusions: There was a strong negative correlation between CVP and IVC collapsibility.

Usefulness of Non-Invasive Parameters (Inferior Vena Cava Diameter, Inferior Vena Cava Collapsibility, Inferior Vena Cava-Aortic Ratio) for Hemodynamic Monitoring in Critically Ill Children: A Systematic Review

“…All studies provided p-value <0.05 for the statistically significant correlation reported. 10,12,[14][15][16][17] In addition to IVC-CI, IVC-DI was assessed by Dalimunthe et al and Aslan et al Both studies also reported a negative correlation between CVP and IVC-DI with strong level (correlation coefficient; r=−0.623, p=0.003) and moderate level (r=−0.412, p=0.004) of correlation, respectively. Those suggested that a higher percentage of IVC-DI could indicate lower CVP in dehydrated or low-volume status in critically ill children.…”

“Ultrasound Derived Inferior Vena Cava Diameter and Collapsibility Index to Predict Central Venous Pressure Prior and After a Fluid Challenge in Spontaneous Breathing Preoperative Patients”

“…Das aditi et al [20] studied the effectiveness of CVP and IVC collapsibility index in predicting fluid responsiveness in paediatric patients with shock. She found that most of the enrolled patients were fluid responders (66%).…”