‘To measure is to know’ (Lord Kelvin)

Abstract

http://onlinelibrary.wiley.com/doi/10.1111/resp.12384/abstract

Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD

“…These data are unique in their comprehensive nature, although the importance of sampling the airway wall has been emphasized as needed to complement more easily obtained luminal cell counts in BAL or sputum . The activation of an innate neutrophil and macrophage reaction in the airway lumen in COPD seems more consistent, although, here too, there have been conflicting reports, as encompassed by previous reviews .…”

Year in review 2015: Asthma and chronic obstructive pulmonary disease

“…Eosinophilic airway inflammation was also examined in another Respirology paper this year and discussed in an accompanying editorial . A Perth‐based group demonstrated that airway smooth muscle remodelling in asthma is present in both small and large airways in most fatal asthma cases.…”

“…33 Eosinophilic airway inflammation was also examined in another Respirology paper this year and discussed in an accompanying editorial. 34,35 A Perth-based group demonstrated that airway smooth muscle remodelling in asthma is present in both small and large airways in most fatal asthma cases. Although some asthma patients did not have smooth muscle remodelling (around a third), they tended to have died with, rather than of, their asthma.…”