To Study the Prevalence of Impaired Fasting Glucose and Its Correlation With Various Anthropometric Variables

Bhalla, Narotam; Mohan, Gurinder; Kaur, Ranjeet; Bansal, Kamaldeep

doi:10.14260/jemds/1750

Cited by 1 publication

(1 citation statement)

References 7 publications

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“…The prevalence of pre-diabetes increased significantly (p<0.05) with increasing age especially in males as revealed through 𝜒 2 test of association. This was also found in studies done on the prevalence of diabetes and pre-diabetes among men and women in China (Yang et al, 2010), Same result was found in the REGICOR study in the Province of Spain (Masiá et al, 2004;Bhalla et al, 2013). However, in this study percentage of women was found to be more in the middle age group which could be related to increased BMI.…”

Section: Discussionsupporting

confidence: 78%

Beneficial effects of RAS blockers in prediabetics with a hypertension-An observational cohort study

al.¹

2022

Int. j. adv. appl. sci.

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Hypertensive patients have a high prevalence of prediabetes and type II Diabetes mellitus. As per International Diabetic Federation, it has been estimated that more than 470 million people will have prediabetes by 2030. Approximately 5-10% of prediabetes progresses to overt diabetes mellitus, with the same proportion converting back to normoglycemia. In patients who are on Renin-Angiotensin System [RAS] blockers either an Angiotensin converting enzyme inhibitor (ACEI) or an Angiotensin receptor blocker (ARB) would slow down the progress of prediabetic state to overt or frank diabetes mellitus. This was a prospective, observational cohort study and a total of 125 hypertensive patients with impaired glucose tolerance were included in the study who were either on ACE inhibitor or ARB monotherapy. An oral Glucose Tolerance Test (GTT) was done at baseline for screening prediabetic patients, then a periodical assessment of glycemic indices, (fasting blood sugar, 2 hr postprandial blood sugar, and glycosylated hemoglobin), lipid profile, and complication status during the study period were evaluated every 3 months for18months. At the end of 1½ years, for patients belonging to the age group 18-54 years the FBS, PPBS, and HbA1C levels decreased significantly when the RAS blocking drugs (ACEIs and ARBs) were used continuously for 1 year and then they got stabilized. The beneficial effect was seen more in the younger age group 18-54 years old patients. Male above 54 years and females above 49 were resistant to the beneficial effects. In hypertensive patients with impaired glucose tolerance, the blockade of RAS with either ACE inhibitor or ARB has a significant preventive effect on the progression of Type II DM. It may be concluded from the finding of the present study that younger hypertensive patients (18-54 years) of either sex if found to be pre-diabetic may be administered ACEI or ARB as suitable for them. The treatment should be continued vigorously for one year and then it may be maintained to continue the beneficial effect.

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Section: Discussionsupporting

confidence: 78%

Beneficial effects of RAS blockers in prediabetics with a hypertension-An observational cohort study

al.¹

2022

Int. j. adv. appl. sci.

View full text Add to dashboard Cite

show abstract

To Study the Prevalence of Impaired Fasting Glucose and Its Correlation With Various Anthropometric Variables

Cited by 1 publication

References 7 publications

Beneficial effects of RAS blockers in prediabetics with a hypertension-An observational cohort study

Beneficial effects of RAS blockers in prediabetics with a hypertension-An observational cohort study

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